ID   A0A384A8L5_BALAS        Unreviewed;       310 AA.
AC   A0A384A8L5;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Protein XRP2 {ECO:0000256|ARBA:ARBA00015771, ECO:0000256|PIRNR:PIRNR037947};
GN   Name=RP2 {ECO:0000313|RefSeq:XP_007183696.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007183696.1};
RN   [1] {ECO:0000313|RefSeq:XP_007183696.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007183696.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- FUNCTION: Acts as a GTPase-activating protein (GAP) for tubulin in
CC       concert with tubulin-specific chaperone C, but does not enhance tubulin
CC       heterodimerization. {ECO:0000256|PIRNR:PIRNR037947}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004342};
CC       Lipid-anchor {ECO:0000256|ARBA:ARBA00004342}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004342}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004423}; Lipid-anchor
CC       {ECO:0000256|ARBA:ARBA00004423}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00004423}.
CC   -!- SIMILARITY: Belongs to the TBCC family. {ECO:0000256|ARBA:ARBA00008848,
CC       ECO:0000256|PIRNR:PIRNR037947}.
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DR   RefSeq; XP_007183696.1; XM_007183634.1.
DR   AlphaFoldDB; A0A384A8L5; -.
DR   STRING; 310752.A0A384A8L5; -.
DR   KEGG; bacu:103000290; -.
DR   CTD; 6102; -.
DR   InParanoid; A0A384A8L5; -.
DR   OrthoDB; 127089at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.160.20.70; -; 1.
DR   Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 1.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR006599; CARP_motif.
DR   InterPro; IPR036850; NDK-like_dom_sf.
DR   InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR   InterPro; IPR039093; XRP2.
DR   PANTHER; PTHR15440:SF0; PROTEIN XRP2; 1.
DR   PANTHER; PTHR15440; XRP2 PROTEIN; 1.
DR   Pfam; PF07986; TBCC; 1.
DR   PIRSF; PIRSF037947; Protein_XRP2; 1.
DR   SMART; SM00673; CARP; 2.
DR   SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 1.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|PIRNR:PIRNR037947};
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468,
KW   ECO:0000256|PIRNR:PIRNR037947};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Myristate {ECO:0000256|ARBA:ARBA00022707};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|PIRNR:PIRNR037947}; Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT   DOMAIN          1..139
FT                   /note="C-CAP/cofactor C-like"
FT                   /evidence="ECO:0000259|PROSITE:PS51329"
FT   BINDING         58..59
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037947-1"
FT   BINDING         75..78
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037947-1"
SQ   SEQUENCE   310 AA;  34558 MW;  6E6D0F3E098A323B CRC64;
     MFSGLKDETV GRLPGKVAGQ QFLIQDCENC NIYIFDHSAT VTIDDCTNCV IFLGPVKGSV
     FFRNCRDCKS ALACQQFRVR DCRKLEVFLC CATQPIIESS SNIKFGCFQW YYPELAFQFK
     DAGLSIFNNT WSNIHDFTPV SGELNWSLLP EDAVIQDHVP LPTTEELKAV RLSTEASRSI
     VPVSRGQRQK NSDESCLVVL FAGDYTIANA RKLIDELVGK GFFLVQTKEV SMKAEDAQRV
     FREKAPDFLP LLNKGPVIAL EFNGDGAVEG CQLIVNEIFS GTKMFVSESK DAASGDVDSF
     YNFADIQWGK
//