ID A0A384AGZ8_BALAS Unreviewed; 295 AA.
AC A0A384AGZ8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Ion channel TACAN {ECO:0000256|ARBA:ARBA00039635};
DE AltName: Full=Transmembrane protein 120A {ECO:0000256|ARBA:ARBA00041456};
GN Name=TMEM120A {ECO:0000313|RefSeq:XP_007186631.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007186631.1};
RN [1] {ECO:0000313|RefSeq:XP_007186631.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007186631.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}. Nucleus inner membrane
CC {ECO:0000256|ARBA:ARBA00004473}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004473}.
CC -!- SIMILARITY: Belongs to the TMEM120 family.
CC {ECO:0000256|ARBA:ARBA00009700}.
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DR RefSeq; XP_007186631.1; XM_007186569.2.
DR AlphaFoldDB; A0A384AGZ8; -.
DR GeneID; 103009153; -.
DR CTD; 83862; -.
DR OrthoDB; 314124at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR012926; TACAN/TMEM120B.
DR PANTHER; PTHR21433:SF1; ION CHANNEL TACAN; 1.
DR PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR Pfam; PF07851; TMPIT; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 295 AA; 34963 MW; 5CCEC6E29BEF4269 CRC64;
MHPPPPGPLG DCLRDWEELQ QDFHGIQETH RLYRLKLEEL TKLQNNCTSS ITRQKKQLQE
LALVLKKCKP SLPSEAEKAA QELENQIKER QGLFFDMEAY LPKQNGLYLS LVLGNVNVTL
LSKQAKFAYK DEYEKFKLYL TIILILISFT CRFLLNSRVT DAAFNFLLVW YYCTLTIRES
ILINNGSRIK GWWVFHHYVS TFLSGVMLTW PDGLMYQKFR NQFLSFSMYQ SFVQFLQYYY
QSGCLYRLRA LGERHTMDLT VEGFQSWMWR GLTFLLPFLF FGHKFHHQQH GSKKE
//
