ID   A0A384AIN8_BALAS        Unreviewed;       583 AA.
AC   A0A384AIN8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=CD166 antigen {ECO:0000256|ARBA:ARBA00015291};
DE   AltName: Full=Activated leukocyte cell adhesion molecule {ECO:0000256|ARBA:ARBA00030009};
GN   Name=ALCAM {ECO:0000313|RefSeq:XP_007187218.1};
OS   Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS   (Balaenoptera davidsoni).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC   Balaenopteridae; Balaenoptera.
OX   NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007187218.1};
RN   [1] {ECO:0000313|RefSeq:XP_007187218.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007187218.1};
RG   RefSeq;
RL   Submitted (JAN-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC       Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC       Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection,
CC       dendrite {ECO:0000256|ARBA:ARBA00004279}.
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DR   RefSeq; XP_007187218.1; XM_007187156.2.
DR   AlphaFoldDB; A0A384AIN8; -.
DR   STRING; 310752.A0A384AIN8; -.
DR   GeneID; 103003981; -.
DR   KEGG; bacu:103003981; -.
DR   CTD; 214; -.
DR   InParanoid; A0A384AIN8; -.
DR   OrthoDB; 5351031at2759; -.
DR   Proteomes; UP000261681; Unplaced.
DR   GO; GO:0030424; C:axon; IEA:UniProtKB-SubCell.
DR   GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   CDD; cd00096; Ig; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   PANTHER; PTHR11973:SF2; CD166 ANTIGEN; 1.
DR   PANTHER; PTHR11973; CELL SURFACE GLYCOPROTEIN MUC18-RELATED; 1.
DR   Pfam; PF08205; C2-set_2; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 5.
DR   PROSITE; PS50835; IG_LIKE; 4.
PE   4: Predicted;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           28..583
FT                   /note="CD166 antigen"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016566081"
FT   TRANSMEM        528..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          125..234
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          245..328
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          347..409
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          416..501
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
SQ   SEQUENCE   583 AA;  64797 MW;  69D99021F780C349 CRC64;
     MASKAASSCR LVFCLLISAA VLRPGLGWYT VNSAYGDTIV MPCRLSVPQN LMFGKWKYEK
     PDGSPVFIAF RSSTKKSVQY DDVPEYKDRL NLSENYTLSI SNAKISDEKR FVCMLVTEDN
     VFEAPTVVKV FKQPSKPEIV SKAPFLETEQ LKKLGECISK DSYPDGNITW YRNGKVLQPL
     EGAVVIIFKK QMDPVTQLYI MTSSLEYKTT KADIQMPFTC SVTYYGPSGQ KTVYSEQAVF
     DIYYPTEQVT IQVLPSKNAI KEGDNITLKC LGNGNPPPEE FLFYLPGQPE GIRSSNTYTL
     ADVRRNATGD YKCSLIDKKS MIASTAITVH YLDLSLNPSG EVTKQIGDAL PVSCTISASR
     NATVVWMKDN IRLRSSPSFS SLHYQDAGNY VCETALQEVE GLKKRESLTL IVEGKPQIKM
     TKKTDPSGLS KTIICHVEGF PKPAIQWTIT GSGSVINQTE ESPYINGRYY SKIIISPEEN
     VTLTCTAENQ LERTVNSLNV SAISIPEHDE ADEISDENKE KVNDQAKLIV GIVVGLLLAA
     LVAGVVYWLY MKKSKTASKH VNKDLGNLEE NKKLEENNHK TEA
//