ID A0A384ALR2_BALAS Unreviewed; 534 AA.
AC A0A384ALR2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Putative glycerol kinase 5 {ECO:0000256|ARBA:ARBA00013787};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase 5 {ECO:0000256|ARBA:ARBA00033026};
GN Name=GK5 {ECO:0000313|RefSeq:XP_007188134.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007188134.1};
RN [1] {ECO:0000313|RefSeq:XP_007188134.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007188134.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate;
CC Xref=Rhea:RHEA:21644, ChEBI:CHEBI:15378, ChEBI:CHEBI:17754,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57597, ChEBI:CHEBI:456216;
CC EC=2.7.1.30; Evidence={ECO:0000256|ARBA:ARBA00001373};
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007188134.1; XM_007188072.1.
DR AlphaFoldDB; A0A384ALR2; -.
DR STRING; 310752.A0A384ALR2; -.
DR GeneID; 103015420; -.
DR KEGG; bacu:103015420; -.
DR CTD; 256356; -.
DR InParanoid; A0A384ALR2; -.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd07793; FGGY_GK5_metazoa; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR037444; GK5_FGGY.
DR PANTHER; PTHR10196:SF68; GLYCEROL KINASE 5-RELATED; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|RefSeq:XP_007188134.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 26..287
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 297..484
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 534 AA; 59545 MW; E1BAAF2C57D25F16 CRC64;
MSGPPTVPEQ TRPEQNAPDP RRAGFVLGLD VGSSVIRCHV YDRAARIRGS SAQKVKSLYP
QAGWVEIDPD ILWLQFVAVI KESVKAAGLE MNQIVGLGIS TQRATFITWD KKTGKHFHNF
ISWQDLRAIE LVKSWNSSLL MKLIHSSCRA LHFVTRSKRF LAASLFTFTT QHVSLRLAWI
LQNLTEVQKA IEEENCCFGT IDTWLLHKLT KGSEFATDFS NASTTGLFDP YEMCWSKLIT
SLLSIPLSLL PPVKDTSHNF GSVDEEIFGV PIPVVALVAD QQSAMFGECC FQTGDVKLTM
GTGTFLDINT GNNPQQSVGG FYPLIGWKIG QEVVCLAEGN AGDTGTAIQW AQQLDLFTDA
AETEKMAKSL EDSEGVYFVP SFSGLQAPLN DPCACASFMG LKSSTNKYHL VRAILESIAF
RNKQLYEVMQ KEIHIPVRKI RADGGVCKNS FVMQMTSDLI NEMIDRPVHV DMSCVGAASL
AGLAVGFWTD KEELKKLRQS EIVFKPQKKW QEYEKNMGNW VKAVKRSMNW YNKT
//
