ID A0A384AMN9_BALAS Unreviewed; 144 AA.
AC A0A384AMN9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Interleukin-3 {ECO:0000256|ARBA:ARBA00019466};
DE AltName: Full=Hematopoietic growth factor {ECO:0000256|ARBA:ARBA00031944};
DE AltName: Full=Mast cell growth factor {ECO:0000256|ARBA:ARBA00030364};
DE AltName: Full=Multipotential colony-stimulating factor {ECO:0000256|ARBA:ARBA00033034};
DE AltName: Full=P-cell-stimulating factor {ECO:0000256|ARBA:ARBA00032468};
GN Name=LOC103019984 {ECO:0000313|RefSeq:XP_007188646.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007188646.1};
RN [1] {ECO:0000313|RefSeq:XP_007188646.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007188646.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-3 family.
CC {ECO:0000256|ARBA:ARBA00008547}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007188646.1; XM_007188584.1.
DR AlphaFoldDB; A0A384AMN9; -.
DR STRING; 310752.A0A384AMN9; -.
DR KEGG; bacu:103019984; -.
DR InParanoid; A0A384AMN9; -.
DR OrthoDB; 5040497at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR GO; GO:0005135; F:interleukin-3 receptor binding; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR002183; IL-3.
DR PANTHER; PTHR48401; INTERLEUKIN-3; 1.
DR PANTHER; PTHR48401:SF1; INTERLEUKIN-3; 1.
DR Pfam; PF02059; IL3; 1.
DR PRINTS; PR00430; INTERLEUKIN3.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
PE 3: Inferred from homology;
KW Cytokine {ECO:0000256|ARBA:ARBA00022514};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..144
FT /note="Interleukin-3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016938131"
SQ SEQUENCE 144 AA; 16286 MW; 6206DE3AFF1C88C9 CRC64;
MSSLPILHRL LFLLALQAPQ AQGATLKTPG TQQCYELNLI REITNDLDKL PVASEDSLNS
NEKRRLMETS LQRPNLEEFL TFATNSLGED SKIMKNLKEI QPILPTAMST KEPILIEKDN
LGDFRVKLKE YLSAIRDSLN CKNT
//
