ID A0A384ANK9_BALAS Unreviewed; 246 AA.
AC A0A384ANK9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=E3 SUMO-protein ligase NSE2 {ECO:0000256|ARBA:ARBA00020923};
DE AltName: Full=E3 SUMO-protein transferase NSE2 {ECO:0000256|ARBA:ARBA00031731};
DE AltName: Full=Non-structural maintenance of chromosomes element 2 homolog {ECO:0000256|ARBA:ARBA00032533};
GN Name=NSMCE2 {ECO:0000313|RefSeq:XP_007188947.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007188947.1};
RN [1] {ECO:0000313|RefSeq:XP_007188947.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007188947.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NSE2 family.
CC {ECO:0000256|ARBA:ARBA00008212}.
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DR RefSeq; XP_007188947.1; XM_007188885.1.
DR AlphaFoldDB; A0A384ANK9; -.
DR STRING; 310752.A0A384ANK9; -.
DR GeneID; 103015802; -.
DR KEGG; bacu:103015802; -.
DR CTD; 286053; -.
DR InParanoid; A0A384ANK9; -.
DR OrthoDB; 2883263at2759; -.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:InterPro.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0019789; F:SUMO transferase activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16651; SPL-RING_NSE2; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR026846; Nse2(Mms21).
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR004181; Znf_MIZ.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR21330:SF1; E3 SUMO-PROTEIN LIGASE NSE2; 1.
DR PANTHER; PTHR21330; UNCHARACTERIZED; 1.
DR Pfam; PF11789; zf-Nse; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51044; ZF_SP_RING; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022895};
KW Ligase {ECO:0000313|RefSeq:XP_007188947.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Telomere {ECO:0000256|ARBA:ARBA00022895};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00452}.
FT DOMAIN 154..240
FT /note="SP-RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51044"
SQ SEQUENCE 246 AA; 27845 MW; 372CAA8C02AA5B75 CRC64;
MPGRSTSSSG STGFISFSGV ESALSSLKNF QSCISSGMDT ASTVALNLVE TQTEVSSEYS
MDKAMVEFAM MDRELNHYLK AVQSTIKHVR EERPEKIPDL KLLVEKKFLA LQNKNSDADF
QNNEKFAQFK QQLKELKKQY GLQADREADG TEGVDEDMIV TQSQTNFICP ITQLEMKKPV
KNKVCGHTYE EEAIVRMIES KHKRKKKACC PKIGCSHTDV RMSDLIQDEA LRRAIESHKK
KHRQSN
//
