ID A0A384AV06_BALAS Unreviewed; 697 AA.
AC A0A384AV06;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=HBS1-like protein {ECO:0000256|ARBA:ARBA00015186};
GN Name=HBS1L {ECO:0000313|RefSeq:XP_007190964.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007190964.1};
RN [1] {ECO:0000313|RefSeq:XP_007190964.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007190964.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007190964.1; XM_007190902.1.
DR AlphaFoldDB; A0A384AV06; -.
DR STRING; 310752.A0A384AV06; -.
DR KEGG; bacu:103017599; -.
DR CTD; 10767; -.
DR InParanoid; A0A384AV06; -.
DR OrthoDB; 5477300at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd16267; HBS1-like_II; 1.
DR CDD; cd04093; HBS1_C_III; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR015033; HBS1-like_N.
DR InterPro; IPR037189; HBS1-like_N_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR PANTHER; PTHR23115:SF188; HBS1-LIKE PROTEIN; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR Pfam; PF08938; HBS1_N; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF109732; HBS1-like domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 260..486
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 216..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 76889 MW; 491B74BF7DB2D626 CRC64;
MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSQRDKPSV VEPVEEYDYE
DLKESSSSLL NHQLSGIDQA RLFSCLDHMR EVLGDAVPDD ILIEAVLKNK FDVQKALSVV
LEQDKMQNLK VKSEGAISTG KIAKGKSIDS QSSRSESELV PKVAKMTVSG KKQTMGFEVP
GVTAEENGHI FHTPQKGHSS EDTSLVSSDV LETASKSALP SHTIQASEEQ SSTPTPVKKS
SKLRQQIDIK AELEKRQGGK QLLNLVVIGH VDAGKSTLMG HLLYLLGNVN KRTMHKYEQE
SKKAGKASFA YAWVLDETGE ERERGVTMDV GMTKFETKTK VIILMDAPGH KDFIPNMITG
AAQADVAVLV VDASRGEFEA GFETGGQTRE HGLLVRSLGV TQLAVAVNKM DQVNWQQERF
QEITGKLGHF LKQAGFKESD VAFIPTSGLS GENLITRSQS SELTKWYKGL CLLEQIDSFK
PPRRSVDKPF RLCVSDVFKD QGSGFCVTGK IEAGYIQTGD RLLAVPPNET CTAKGITLHD
EPVDWAAAGD HVSLTLVGMD VIKINVGCIF CGPKEPIKVC TRFRARILIF NIEIPITKGF
PVLLHYQTVS EPAVVKRLIS VLNKSTGEVT KKKPKLLTKG QNALVELQTQ RPVALELYKD
FKELGRFMLR YSGSTIAAGV VTEVAWNGTH DISEIKD
//
