ID A0A384AW04_BALAS Unreviewed; 404 AA.
AC A0A384AW04;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Caspase-1 {ECO:0000313|RefSeq:XP_007191299.1};
GN Name=CASP1 {ECO:0000313|RefSeq:XP_007191299.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007191299.1};
RN [1] {ECO:0000313|RefSeq:XP_007191299.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007191299.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
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DR RefSeq; XP_007191299.1; XM_007191237.1.
DR AlphaFoldDB; A0A384AW04; -.
DR SMR; A0A384AW04; -.
DR STRING; 310752.A0A384AW04; -.
DR GeneID; 103013120; -.
DR KEGG; bacu:103013120; -.
DR CTD; 834; -.
DR InParanoid; A0A384AW04; -.
DR OrthoDB; 2873736at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR CDD; cd08325; CARD_CASP1-like; 1.
DR CDD; cd00032; CASc; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR001315; CARD.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR033139; Caspase_cys_AS.
DR InterPro; IPR016129; Caspase_his_AS.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR002138; Pept_C14_p10.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR47901; CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18; 1.
DR PANTHER; PTHR47901:SF3; CASPASE-1; 1.
DR Pfam; PF00619; CARD; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR PIRSF; PIRSF038001; Caspase_ICE; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00114; CARD; 1.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50209; CARD; 1.
DR PROSITE; PS01122; CASPASE_CYS; 1.
DR PROSITE; PS01121; CASPASE_HIS; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 1..91
FT /note="CARD"
FT /evidence="ECO:0000259|PROSITE:PS50209"
FT DOMAIN 161..289
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
FT DOMAIN 317..402
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
SQ SEQUENCE 404 AA; 45298 MW; 275562EDE45F4D80 CRC64;
MADKVLKEKR NLFVHSVGMG TINGLLDELL EKRVLNQAEM EKVRDENATV MDKARALIDS
VIPKGSQACQ ICISHIREDD SLLAGTLGLS SGSQSGNYLN TQESQAVVPP FPAPQAMQDN
PVKLASSGPE GNLKLCPLET AQRIWKEKSA EIYPIMERSI RTRIALIICN TEFENLPRRD
GADVDIRNMK MLLEGLGYSV DVKENLTASD MTIELKSFAA RPEHRTSDST FLVLMSHGIR
TGVCGKKYSE EVPDVLKVNT IFQILNTWNC PSLKDKPKVI IIQACRGENQ GVVWLKDSVE
ASGNCSLLAP EDFEDDAIKK AHVEKDFIAF CSSTPDNVSW RHPILGSLFI IKLIENFQEY
AWFCDLEEIF RKVRFSFELP DGKAQMPTAE RVTLTRCFYL FPGY
//
