ID A0A384AYF1_BALAS Unreviewed; 900 AA.
AC A0A384AYF1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Prickle-like protein 2 isoform X1 {ECO:0000313|RefSeq:XP_007192456.1};
GN Name=PRICKLE2 {ECO:0000313|RefSeq:XP_007192456.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007192456.1};
RN [1] {ECO:0000313|RefSeq:XP_007192456.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007192456.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the prickle / espinas / testin family.
CC {ECO:0000256|ARBA:ARBA00008268}.
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DR RefSeq; XP_007192456.1; XM_007192394.2.
DR AlphaFoldDB; A0A384AYF1; -.
DR STRING; 310752.A0A384AYF1; -.
DR GeneID; 103011601; -.
DR KEGG; bacu:103011601; -.
DR CTD; 166336; -.
DR InParanoid; A0A384AYF1; -.
DR OrthoDB; 370973at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09415; LIM1_Prickle; 1.
DR CDD; cd09418; LIM2_Prickle; 1.
DR CDD; cd09420; LIM3_Prickle; 1.
DR CDD; cd09827; PET_Prickle; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 3.
DR InterPro; IPR033725; LIM1_prickle.
DR InterPro; IPR033726; LIM2_prickle.
DR InterPro; IPR033727; LIM3_prickle.
DR InterPro; IPR010442; PET_domain.
DR InterPro; IPR033723; PET_prickle.
DR InterPro; IPR047120; Pk/Esn/Tes.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24211; LIM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24211:SF18; PRICKLE-LIKE PROTEIN 2; 1.
DR Pfam; PF00412; LIM; 3.
DR Pfam; PF06297; PET; 1.
DR SMART; SM00132; LIM; 3.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 2.
DR PROSITE; PS51303; PET; 1.
PE 3: Inferred from homology;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 74..182
FT /note="PET"
FT /evidence="ECO:0000259|PROSITE:PS51303"
FT DOMAIN 184..248
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT DOMAIN 249..309
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 370..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 878..900
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..405
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..770
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 900 AA; 102033 MW; 21BD9EAE293C2E31 CRC64;
MFSRSSRKRL SSRSLTGLGR IERGQPCNAC GDQCPGFALH KWRKICLHCK CPQEEHMVTV
MPLAMEKTVS KLMFDFQRNS TSDDDSGCAL EEYAWVPPGL KPEQVHQYYS CLPEEKVPYV
NSPGEKLRIK QLLHQLPPHD NEVRYCNSLD EEEKRELKLF SNQRKRENLG RGNVRPFPVT
MTGAICEQCG GQINGGDIAV FASRAGHGVC WHPPCFICTV CNELLVDLIY FYQDGKIYCG
RHHAECLKPR CAACDEIIFA DECTEAEGRH WHMKHFCCFE CETVLGGQRY IMKEGRPYCC
HCFESLYAEY CDTCAQHIGI DQGQMTYDGQ HWHATETCFC CAHCKKSLLG RPFLPKQGQI
FCSRACSAGE DPNGSDSSDS AFQNARAKES RRSAKIGKNK GKTEEPMLNQ HSQLQVSSNR
LSADVDPLSL QMDLLSLSSQ TPSLNRDPIW RSRDEPYHYG NKMEQSQSQS PLQLLSQCNI
RTSYSPGGQG AGAQPDMWAK HFSNPKRSSS LAMKGHGGSF IKECREDYYP GRLRSQESYS
DMSSQSFSEN RGSIQVPKYE EEEEEEGGMS TQQCRTRHPI SSLKYTEDMT PTEQTPRGSM
ESLALSNTTG LSADGGAKRQ EHLSRFSMPD LSKDSGMNVS EKLSNMGTLN SSMQFRSAES
VRSLLSAQQY QEMEGNLHPL SNPIRYRDLQ AHGRMHQSFD FDGGMAGSKL PGPEGVRMQP
MSERTRRRAT SREDNRRFRP HRSRRSRRSR SDNALHLASE REAISQLKER PPLRAREDYD
QFMRQRSFQE SLGQGSRRDL YGRCPRTVSD LALQNAFGER WGPYFTEYDW CSTCSSSSES
DNEGYFLGEP IPQPAHLRYV TSDELLHKYS SYGLPKSSTL GGRGQLHSRK RQKSKNCIIS
//
