ID A0A384B2Y2_BALAS Unreviewed; 829 AA.
AC A0A384B2Y2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Patched domain-containing protein 4 {ECO:0000313|RefSeq:XP_007193913.1};
GN Name=PTCHD4 {ECO:0000313|RefSeq:XP_007193913.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007193913.1};
RN [1] {ECO:0000313|RefSeq:XP_007193913.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007193913.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR RefSeq; XP_007193913.1; XM_007193851.1.
DR AlphaFoldDB; A0A384B2Y2; -.
DR STRING; 310752.A0A384B2Y2; -.
DR GeneID; 102997293; -.
DR KEGG; bacu:102997293; -.
DR CTD; 442213; -.
DR InParanoid; A0A384B2Y2; -.
DR OrthoDB; 2876883at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796:SF15; PATCHED DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 246..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 644..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 696..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 741..759
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..793
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..375
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 829 AA; 94236 MW; 8B79C656E2B291FB CRC64;
MLRQVLRRGL RSFCHRLGLC VSRHPVFFLT VPAVLTITFG LSALNRFQPE GDLERLVAPS
HSLAKIERSL ASSLFPLDQS KSQLYSDLHT PGRYGRVILL SPPGDNILLQ AEGILQTHRA
VLEMKDGRNS FIGHQLGGVV EVPNSKDQRV KSARAVQITY YLQTYGSATQ DLIGEKWENE
FCKLVRKLQE EHQDLQLYSL ASFSLWRDFH KTSVLARSKV LVSLVLILTT ATLSSSMKDC
LRGKPFLGLL GVLTVCISIV TAAGIFFITD GKYNSTLLGI PFFAMGHGTK GVFELLSGWR
RTKENLPFKD RVADAYSDVM VTYTMTSSLY FITFGMGASP FTNIEAVKVF CQNMCVSILL
NYFYIFSFFG SCLVFAGQLE QNRYHSIFCC KIPSAEYLDR KPVWFQTVMS DGHQQTSHHE
TNPYQHHFIQ HFLREHYNEW ITNIYVKPFV VILYLIYASF SFMGCLQISD GANIISLLAS
DSPSVSYAMV QQKYFSNYSP VIGFYVYEPL EYWNSSVQQD LRRLCSGFTA VSWVEQYYQF
LKVSNISANN KSDFISVLQS SFLKKPEFQH FRNDIIFSKA GDENSIIASR LYLVARTSRD
KQKEVIEVLE KLRPLSLSKS IRFIVFNPSF VFMDHYSLSV TVPVLIAGFG VLLVLILTFF
LVIHPLGNFW LILSVTSIEL GVLGLMTLWN IEMDCIAILC LIYTLNFAID HCAPLLYTFV
LATEHTRTQC IKSSLQEHGT AILQNVTSFL IGLVPLLFVP SNLTFTLFKC LLLMGGCTLL
HCFVILPVFL TFFPPSKKHH KKKKRAKRKE REEIECIEIQ ENPDHVTTV
//
