ID A0A384B423_BALAS Unreviewed; 414 AA.
AC A0A384B423;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=RNA exonuclease 4 {ECO:0000256|ARBA:ARBA00016937};
GN Name=REXO4 {ECO:0000313|RefSeq:XP_007194466.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007194466.1};
RN [1] {ECO:0000313|RefSeq:XP_007194466.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007194466.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the REXO4 family.
CC {ECO:0000256|ARBA:ARBA00010489}.
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DR RefSeq; XP_007194466.1; XM_007194404.1.
DR AlphaFoldDB; A0A384B423; -.
DR STRING; 310752.A0A384B423; -.
DR GeneID; 102999350; -.
DR KEGG; bacu:102999350; -.
DR CTD; 57109; -.
DR InParanoid; A0A384B423; -.
DR OrthoDB; 5479236at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR CDD; cd06144; REX4_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR037431; REX4_DEDDh_dom.
DR InterPro; IPR047021; REXO1/3/4-like.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR12801:SF45; RNA EXONUCLEASE 4; 1.
DR PANTHER; PTHR12801; RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839,
KW ECO:0000313|RefSeq:XP_007194466.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839,
KW ECO:0000313|RefSeq:XP_007194466.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839,
KW ECO:0000313|RefSeq:XP_007194466.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 236..397
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
FT REGION 1..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..41
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 414 AA; 46019 MW; 66C9C3BD12BC6F2C CRC64;
MAKARVLAPE RAPGDPAPEP GLVKKPNRKK NRKKRFWKNK AREAGRKPGN GPGVVMVRPP
KAPEDFSQNW KALQEELLKQ KSQAPEEPLV LSQTDSKKQP QSVQQNRKVI SDKAKRDEMG
TENTDPKAAG SSVPSGCLVN RKIQAQRNEK GAKKRTNDDI FPKREVKRKK WKAEEVTATL
PPVPPTDEDI WFDDVDPADI EAAIGPEAAR IARKRLGQSE SSITLVKERA FGGLTKALAA
DCEMVGVGPR GEDSIVARVS LVNQYGKCVY DKYVKPTQPV TDYRTAVSGI RPDDLAQGEE
FEVVQKEVAD LLKGRILVGH ALHNDLKALF LGHPKKKIRD TQKYKPFRSQ VKSGRPSLKL
LAERVLGIRV QQAEHCSIQD AQAAMRLYVL VKKEWESIAR DRRPPASKAH GDAA
//
