ID A0A384BAH1_BALAS Unreviewed; 772 AA.
AC A0A384BAH1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 08-NOV-2023, entry version 17.
DE SubName: Full=Microprocessor complex subunit DGCR8 isoform X2 {ECO:0000313|RefSeq:XP_007196299.1};
GN Name=DGCR8 {ECO:0000313|RefSeq:XP_007196299.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007196299.1};
RN [1] {ECO:0000313|RefSeq:XP_007196299.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007196299.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
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DR RefSeq; XP_007196299.1; XM_007196237.1.
DR AlphaFoldDB; A0A384BAH1; -.
DR CTD; 54487; -.
DR OrthoDB; 5404886at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0070877; C:microprocessor complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031053; P:primary miRNA processing; IEA:InterPro.
DR CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR CDD; cd19868; DSRM_DGCR8_rpt2; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.160.590; -; 1.
DR InterPro; IPR040375; DGCR8.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR13482:SF3; MICROPROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR PANTHER; PTHR13482; MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 301..334
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 511..578
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 360..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 85792 MW; 55D87E75777A97E4 CRC64;
METCESPSPL PREPAGGAVM ENQACPLRAL PRGQSPPPPL QTSSDAEVMD VGSGGDGQAE
PPAEDPLNFY GASLLSKGSF SKARLLVDPN CSGHSPRTAR HAPAVRKFSP DLKLLKDVKI
SVSFTESCRS KDRKVLYTGA ERDARAECGL ALSPVSGDVH ACPFGGSVGN GVGVGGESAD
KKDEENELDQ EKRVEYAVLD ELEDFTDNLE LDEEGAGGLT AKAIVQRDRV DEEALKFSYE
DDFDNDVDAL LEEGLCAPKK RRMEEKYGGD SDHPSDGETS VQPMMTKIKT VLKSRGRPPT
EPLPDGWIMT FHNSGVPVYL HRESRVVTWS RPYFLGTGSI RKHDPPLSSI PCLHYKKMKD
NEEREQNSEL SPCGEVSPAK PLSRSAELEL PLEDPDSLGA DLGPPDEKDP LGAEAAPGAL
GQVKAKVEVC KDESVDLEEF RNYLEKRFDF EQVTVKKFRT WAERRQFNRE MKRKQAESER
PILPANQKLI TLSVQDAPTK KEFVINPNGK SEVCILHEYM QRVLKVRPVY NFFECENPSE
PFGASVTIDG VTYGSGTASS KKLAKNKAAR ATLEILIPDF VKQTSEEKPK DSEELEYFNH
ISIEDSRVYE LTSKAGLLSP YQILHECLKR NHGMGDTSIK FEVVPGKNQK SEYVMACGKH
TVRGWCKNKR VGKQLASQKI LQLLHPHVKN WGSLLRMYGR ESSKMVKQTS DKSVIELQQF
ARKNKPNLHI LSKLQEEMRR LAEEREETRK KPKMSIVASA QPGGEPLCTV DV
//
