ID A0A384BAT3_BALAS Unreviewed; 495 AA.
AC A0A384BAT3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN Name=PTPN2 {ECO:0000313|RefSeq:XP_007196409.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007196409.1};
RN [1] {ECO:0000313|RefSeq:XP_007196409.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007196409.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class 1 subfamily. {ECO:0000256|ARBA:ARBA00009701}.
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DR RefSeq; XP_007196409.1; XM_007196347.1.
DR AlphaFoldDB; A0A384BAT3; -.
DR STRING; 310752.A0A384BAT3; -.
DR KEGG; bacu:103014463; -.
DR CTD; 5771; -.
DR InParanoid; A0A384BAT3; -.
DR OrthoDB; 2911650at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46047:SF1; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 2; 1.
DR PANTHER; PTHR46047; TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F; 1.
DR Pfam; PF00025; Arf; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 125..383
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 298..374
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 57418 MW; FE4E7FEC6FC914DD CRC64;
MPAQGRVPAI AWERGKEEHS QSWAGAGGSG RMESCRRVPE ELPPERQDQQ EIVTGARRHR
WGRSRHRRDV RLTLKAQDRL PRETRIPEAV VFVVDSSHRD RVSEAHNELA KLLTEKELRD
ALLLIFANKQ EIRSESHDYP HRVAKFPENR NRNRYRDVSP YDHSRVKLQN AENDYINASL
VDIEEAQRSY ILTQGPLPNT GCHFWLMVWQ QKTKAVVMLN RIVEKESVKC AQYWPTKDDR
EMLFKETGFS VKFLSEDVKS YYTVHVLQLG NTNSGETRTI SHFHYTTWPD FGVPESPASF
LNFLFKVRES GSLNPEHGPA VIHCSAGIGR SGTFSLVDTC LVLMEKGDNI NIKQLLLNMR
KYRMGLIQTP DQLRFSYMTI IEGAKFIKGD SSIQKRWKEL SKEDVCPVFD HSPTKIMTEK
YNGNRIGLEE EKLTSDRYTG LSSKMQDMLE ENSESALRKR LREDRKASTA QKVQQMKKRL
NETERKRKRP RLTDT
//
