ID A0A384BAW0_BALAS Unreviewed; 99 AA.
AC A0A384BAW0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=FXYD domain-containing ion transport regulator {ECO:0000256|RuleBase:RU364131};
GN Name=FXYD2 {ECO:0000313|RefSeq:XP_007196638.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007196638.1};
RN [1] {ECO:0000313|RefSeq:XP_007196638.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007196638.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in forming the receptor site for cardiac
CC glycoside binding or may modulate the transport function of the sodium
CC ATPase. {ECO:0000256|ARBA:ARBA00034654}.
CC -!- SUBUNIT: Regulatory subunit of the sodium/potassium-transporting ATPase
CC which is composed of a catalytic alpha subunit, an auxiliary non-
CC catalytic beta subunit and an additional regulatory subunit.
CC {ECO:0000256|ARBA:ARBA00034793}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004183}; Single-
CC pass type III membrane protein {ECO:0000256|ARBA:ARBA00004183}.
CC -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000256|ARBA:ARBA00005948,
CC ECO:0000256|RuleBase:RU364131}.
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DR RefSeq; XP_007196638.1; XM_007196576.2.
DR AlphaFoldDB; A0A384BAW0; -.
DR GeneID; 102999896; -.
DR CTD; 486; -.
DR OrthoDB; 4637393at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0043269; P:regulation of monoatomic ion transport; IEA:InterPro.
DR CDD; cd20318; FXYD2; 1.
DR Gene3D; 1.20.5.780; Single helix bin; 1.
DR InterPro; IPR047282; ATNG.
DR InterPro; IPR047297; FXYD_motif.
DR InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR PANTHER; PTHR14132; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA; 1.
DR PANTHER; PTHR14132:SF3; SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT GAMMA; 1.
DR Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR PROSITE; PS01310; FXYD; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU364131};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364131};
KW Reference proteome {ECO:0000313|Proteomes:UP000261681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364131};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364131};
KW Transport {ECO:0000256|RuleBase:RU364131}.
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 99 AA; 10916 MW; BC3B9D53F4943BB6 CRC64;
MSQKRLEEQE PGTVPEAEAA GRGQWDVPGL RGDMAGLSTD DGGSPKEDVD PFSYDYETVR
NGGLIFAALA FIVGLIIILS RRFRCGGRKK HRQVHEDEL
//
