ID A0A384BEU4_BALAS Unreviewed; 1488 AA.
AC A0A384BEU4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Nuclear factor of activated T-cells 5 isoform X1 {ECO:0000313|RefSeq:XP_007198262.1};
GN Name=NFAT5 {ECO:0000313|RefSeq:XP_007198262.1};
OS Balaenoptera acutorostrata scammoni (North Pacific minke whale)
OS (Balaenoptera davidsoni).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti;
OC Balaenopteridae; Balaenoptera.
OX NCBI_TaxID=310752 {ECO:0000313|Proteomes:UP000261681, ECO:0000313|RefSeq:XP_007198262.1};
RN [1] {ECO:0000313|RefSeq:XP_007198262.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007198262.1};
RG RefSeq;
RL Submitted (JAN-2023) to UniProtKB.
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DR RefSeq; XP_007198262.1; XM_007198200.1.
DR STRING; 310752.A0A384BEU4; -.
DR KEGG; bacu:103004692; -.
DR CTD; 10725; -.
DR InParanoid; A0A384BEU4; -.
DR OrthoDB; 5405363at2759; -.
DR Proteomes; UP000261681; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd01178; IPT_NFAT; 1.
DR CDD; cd07882; RHD-n_TonEBP; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR015646; NFAT5_RHD_DNA-bd.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF10; NUCLEAR FACTOR OF ACTIVATED T-CELLS 5; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR PRINTS; PR01789; NUCFACTORATC.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261681}.
FT DOMAIN 217..396
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 912..950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1045..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1152..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1277..1328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1428..1459
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1152..1236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1488 AA; 161004 MW; A0C4421EB62DC419 CRC64;
MSQTSGGEAG SPPPAVVAAD ASSAPSSSSM GGACSSFTTS SSPTIYSTSV TDSKAMQVES
CSSALGVSNR GVSEKQLTSN TVQQHPSTPK RHTVLYISPP PEDLLDNSRM SCQDEGCGLE
SEQSCSMWME DSPSNFSNMS TSSYNDNTEV PRKSRKRNPK QRPGVKRRDC EESNMDIFDA
DSAKAPHYVL SQLTTDNKGN SKAGNGTLEN QKGTGVKKSP MLCGQYPVKS EGKELKIVVQ
PETQHRARYL TEGSRGSVKD RTQQGFPTVK LEGHNEPVVL QVFVGNDSGR VKPHGFYQAC
RVTGRNTTPC KEVDIEGTTV IEVGLDPSNN MTLAVDCVGI LKLRNADVEA RIGIAGSKKK
STRARLVFRV NITRKDGSTL TLQTPSSPIL CTQPAGVPEI LKKSLHSCSV KGEEEVFLIG
KNFLKGTKVI FQENVSDENS WKSEAEIDME LFHQNHLIVK VPPYHDQHIT LPVSVGIYVV
TNAGRSHDVQ PFTYTPDPAA AAALNVNVKK EISSPARPCS FEEAMKAMKT AGCNLDKVNI
LPNALITPLI SSSVIKSEDV TPMEVTAEKR SSPIFKTTKT VGSTQQTLEN ISNIAGNGSF
SSSSSSSHLP SENEKQQQIQ PKAYNPETLT TIQTQDISQP GTFPAVSASS QLPNSDALLQ
QATQFQTRET QSREVLQSDG TVVNLSHLTE ASQQQQQSPL QEQAQTLQQQ ISSNIFPSPN
SVSQQLQNTI QQLQAGSFTG STTSGSNGNV DLVQQVLEAQ QQLSSVLFSA PDGNENVQEQ
LSADIFQQVS QIQNSVSPGM FSSTEPAVHT RPDNLIAGRA ESVHPQNENT LSNQQQQQQQ
QQVMESSAAM VIEMQQSICQ AAAQIQSELF PSTASANGNL QQSPVYQQTS HMMSALSANE
DMQMQCELFS SPPAVSGNET ATTTTQQVAT PGTTMFQTSS SADGEETGAQ AKQIQNSVFQ
TMVQMQHSGD SQPQVNLFSS TKSMISVQNN GTQQQGNGLF QQGNEMMSLQ SGNFLQQSSH
SQAQLFHPQN PIADAQNLSQ ETQGSIFHSP SPIVHSQTST TSSEQMQPPM FHSQNTMAVL
QGSSVPQDQQ SANIFLSQSP MNNLQTNTVA QEEQISFFAA QNSISPLQST SNTEQQAAFQ
QQAPISHIQT PMLSQEQAQP SQQGLFQPQV SLGSLPPNPM PQNQQGTIFQ SQHSMVAIQS
NSASQEQQQQ QQQQQQQQQQ QQQSILFSNQ NAMAPMASQK PPPPNMIFNP SQNPMANQEQ
QNQSIFHQQN NMAPMNQEQQ PMQFQNQPTV SSLQNPGPTQ SESSQTSLFH SSPQIQLVQG
SPSSQEQQVT LFLSPASMSA LQNSINQQDM QQSPLYSPQN NMPGIQGATS SPQPQATLFH
NTTGGTMNQL QNSPGSSQQT SGMFLFGIQN NCSQLLTSGP ATLPDQLMAI SQPGQPQNEG
QPPVTTLLSQ QMPENSPLAS SINTNQNIEK IDLLVSLQNQ GNNLTGSF
//
