ID   A0A384BHF8_URSMA        Unreviewed;       289 AA.
AC   A0A384BHF8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Retinol dehydrogenase 16 isoform X3 {ECO:0000313|RefSeq:XP_008682007.1};
GN   Name=RDH16 {ECO:0000313|RefSeq:XP_008682007.1};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008682007.1};
RN   [1] {ECO:0000313|RefSeq:XP_008682007.1}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008682007.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|RuleBase:RU000363}.
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DR   RefSeq; XP_008682007.1; XM_008683785.2.
DR   AlphaFoldDB; A0A384BHF8; -.
DR   GeneID; 103656387; -.
DR   CTD; 8608; -.
DR   OrthoDB; 5403248at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43313:SF11; RETINOL DEHYDROGENASE 16; 1.
DR   PANTHER; PTHR43313; SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680}.
SQ   SEQUENCE   289 AA;  32547 MW;  4329EF7DF39BA3E4 CRC64;
     MWLYAAALVG LCYLLRWYRE KQVVSHLRDK YVFITGCDSG FGHLLARQLD LRGLRVLAAC
     LTEKGAQQLR AQTSDRLETV ILDVTKTESI SAATQWVKER VGDRGLWGLV NNAGISIPTA
     PNEWLTKHDF MKILDVNLLG LLEVTLSLLS LVRKARGRVV NVSSVVGRVS LLGGGYCISK
     YGVEAFSDSL RRELSYFGVK VALIEPGFFK TNVTSPEKIS RAIQEAWDRV SPEVKDIYGE
     KFLASACHPR TRYSPGWDAK LLFIPMSYMP TWLVDAMMYW RSPRPIKAL
//