ID A0A384BLG8_URSMA Unreviewed; 538 AA.
AC A0A384BLG8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sialic acid-binding Ig-like lectin 5 {ECO:0000313|Ensembl:ENSUMAP00000013985};
GN Name=SIGLEC14 {ECO:0000313|Ensembl:ENSUMAP00000013985};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Ensembl:ENSUMAP00000013985};
RN [1] {ECO:0000313|Ensembl:ENSUMAP00000013985}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. SIGLEC (sialic
CC acid binding Ig-like lectin) family. {ECO:0000256|ARBA:ARBA00038361}.
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DR RefSeq; XP_008682959.1; XM_008684737.1.
DR RefSeq; XP_008682960.1; XM_008684738.1.
DR AlphaFoldDB; A0A384BLG8; -.
DR Ensembl; ENSUMAT00000016587.1; ENSUMAP00000013985.1; ENSUMAG00000010295.1.
DR GeneID; 103657306; -.
DR KEGG; umr:103657306; -.
DR OrthoDB; 5350608at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12035:SF99; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12035; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Lectin {ECO:0000256|ARBA:ARBA00022734};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 15..99
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 137..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 227..324
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 538 AA; 58092 MW; 1CEB167CF5768365 CRC64;
MPLWLLFVLW GGPLPQALSY QLELQESVTV QEALCVHVPC KFSYPWLSFA APHMSWFQKG
ADVSRDPPVA TSKPNQKLHE RTQGRFFLRG DPQSHDCSLD IMGVNMGDSG TYFFQMGTYS
YLDNMLSLNV TALTHTPDIL IPETLEHGRP GNLTCSVPWA CEQGTPPIFS WTSAALTALG
PRTHLSSVLT LTPRPQDHGT NLACQVYFPA AGVTVERTSQ LDVTYAPQNT AIRIFHGNRT
ALGTLQNTSS ILIREGQALR LRCTADSNPP AELSWFWGSP TLNATPICKS PILDLPQVGA
EEEGDLTCQA QNSLGSQQVS LHLSVVYALW LLPASCSWEG EGLHCNCSSR ARPAPTLRWR
LGEGLLEGNH SNASWTVTSS SAGPWANSSL SLSGPLVSGL RLSCEAGNAH GSQSAAILLL
PGKPEPRASG VLGAVGGAGI MALLSLCLCL VFRVKTCRKK AVKPVRSLNL NLAGSAGSGA
HQQQSWMDIP AGHPAPAEAS PVSGENQELH YAFLRFPKLK PHEQQGINTE YSEIKIHK
//
