ID A0A384BQT4_URSMA Unreviewed; 972 AA.
AC A0A384BQT4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 2.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Serine/threonine-protein kinase 31 isoform X2 {ECO:0000313|RefSeq:XP_008684624.2};
GN Name=STK31 {ECO:0000313|RefSeq:XP_008684624.2};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008684624.2};
RN [1] {ECO:0000313|RefSeq:XP_008684624.2}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008684624.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008684624.2; XM_008686402.2.
DR AlphaFoldDB; A0A384BQT4; -.
DR OrthoDB; 5315644at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd20430; Tudor_TDRD8; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.40.50.90; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047383; Tudor_TDRD8.
DR PANTHER; PTHR48008; LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE IMK3-RELATED; 1.
DR PANTHER; PTHR48008:SF6; LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE IMK3-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF00567; TUDOR; 1.
DR SMART; SM00333; TUDOR; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF50199; Staphylococcal nuclease; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50304; TUDOR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000313|RefSeq:XP_008684624.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Transferase {ECO:0000313|RefSeq:XP_008684624.2}.
FT DOMAIN 55..114
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 687..972
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 931..972
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 287..321
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 613..654
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 935..972
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 972 AA; 110965 MW; 7FE34C8D5D105C6C CRC64;
MDEDMHYNKV EDVVGSHVED AVTFWAQSIN RNKDIMKIGC SLSEVCPHAN SVFGNLDPKK
IYGGLFSEDK CWYRCKVLKI ISDEKCLVRY IDYGNTEILN RSDIVEIPLD LQFSSVAKKY
RLWGLQIPSG QEVTQFDQGR TFLGSLIFEK EIKMRIKATY QDGTVIAQAE YGSVDIGEEV
AKKGFAEKCK LASSTNTCEE KKSDPGQLVL RNLKSPIPSW GHRSNQSAFT RPKGRLSGRM
TLDLKNENDA GNHVTFPKEN LTVGDFNLGS NVSLAKIKQD QKLIEENERL KTEKEVLLES
YKALESKVEQ TAQELQQEKA TTMDLTKHLE STLKTHVGTR MENLAAKVEI LKEIRHVNIN
VRFGKDLSDA MQVLDEECFT TPASLTELER IWAEYNLAQE NIKTCENVNE GNILIAKRNE
VQQKLNMAVE VFILEVDELP LNKRLKTLQD LSTSLEAVYG QAKEGTNSEE ILKKFYVWKC
DKREEFTSVR NETEVSLQRL VAWFQNTVKA FDLSVEESQT SEDTISSLDE ILEKSESSVC
KELEISLIEQ GDADKEIILN TYSQVLQKIR SEERLIAIVQ SKYKDSIEFK KQIIECLNKS
PSVDHLLSIK KTLKNLKARL RWKLVEKNNL EESDDHDESE IEKIKQEITQ LRDRVFQEIY
REQEEYEKLN SLVQKWFPEL PLLYPEIGLL KYMNSGGLLT MSLERDLLDA EPMKELSSKR
PLVCSEVNGK IILLKGYSVD VDTEARVIQR AAAYHRAWRK TKEESGLLPL IFLFLCKSDP
MAYLMVPYYP RANLSAVQAS VPLTSEEALK VMKGVAQGLH TLHKADIIHG SLHQNNVFAL
NREQGIVGDF DFTKSGSQRA SVNMVVGDLS LISPELKMGK PASPSSDLYA YGCLLLWDYN
IKSLLYSLIY SRSSMTAEQV LNAECFLVPK GKSTPNSEKD TEYNQYKEKE ELKMENLDKY
KEKTRNYESD FD
//
