ID A0A384BWR1_URSMA Unreviewed; 456 AA.
AC A0A384BWR1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Protein unc-93 homolog A {ECO:0000256|ARBA:ARBA00040854};
GN Name=UNC93A {ECO:0000313|RefSeq:XP_008686684.2};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008686684.2};
RN [1] {ECO:0000313|RefSeq:XP_008686684.2}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008686684.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the unc-93 family.
CC {ECO:0000256|ARBA:ARBA00009172}.
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DR RefSeq; XP_008686684.2; XM_008688462.2.
DR AlphaFoldDB; A0A384BWR1; -.
DR STRING; 29073.ENSUMAP00000015635; -.
DR KEGG; umr:103660802; -.
DR OrthoDB; 1275866at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR CDD; cd17406; MFS_unc93A_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19444:SF13; PROTEIN UNC-93 HOMOLOG A; 1.
DR PANTHER; PTHR19444; UNC-93 RELATED; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 456 AA; 50069 MW; 2EA3F844F6819694 CRC64;
MERSLKNVLV VSFGFLLLFT AYGGLQSLQS SLYSEEGLGV TALSTLYGGV LLSSMFLPPL
LIKKFGCKWT IVISMCCYVA FSLGNFYASW YTLIPTSILL GLGAAPLWSA QCTYLTIMGN
TQAEKVGKVG RDVVNQYFGI FFLIFQSSGV WGNLISSLVF GQTPTQEAIP EEQLLSCGAS
DCLMATASTN STQRPSQTLI YTLLGIYTGS GVLAVLLVAV FLEPIKDAQQ KSEGEKELPF
WSTLLSTFRL LRDRRLRLLV LLPMYSGFEQ AFLAGDYTRS YTTCALGIQF VGYVMICFSA
TNSLCSMLYG RLSQHTGRIA LYALGAVTHL SCIIALLLWK PHPHQLAVFF VFSGLWGVAD
AVWQTQNNVL YGVLFQKSKE AAFANYRLWE ALGFVIAFGY STFLCVNVKL YVLLGVLSLT
MLAYGTVEYL EAKKPARPVA TEQTKTADGA ETETAM
//
