ID A0A384BZY5_URSMA Unreviewed; 647 AA.
AC A0A384BZY5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Zinc finger protein 202 {ECO:0000313|Ensembl:ENSUMAP00000031117, ECO:0000313|RefSeq:XP_008688158.1};
GN Name=ZNF202 {ECO:0000313|Ensembl:ENSUMAP00000031117,
GN ECO:0000313|RefSeq:XP_008688158.1, ECO:0000313|RefSeq:XP_040487030.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008688158.1};
RN [1] {ECO:0000313|Ensembl:ENSUMAP00000031117}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008688158.1, ECO:0000313|RefSeq:XP_040487030.1}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008688158.1,
RC ECO:0000313|RefSeq:XP_040487030.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008688158.1; XM_008689936.2.
DR RefSeq; XP_040487030.1; XM_040631096.1.
DR STRING; 29073.ENSUMAP00000031117; -.
DR Ensembl; ENSUMAT00000036757.1; ENSUMAP00000031117.1; ENSUMAG00000022464.1.
DR GeneID; 103662279; -.
DR KEGG; umr:103662279; -.
DR CTD; 7753; -.
DR OMA; ELYLCNE; -.
DR OrthoDB; 5249345at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR CDD; cd07765; KRAB_A-box; 1.
DR CDD; cd07936; SCAN; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR003309; SCAN_dom.
DR InterPro; IPR038269; SCAN_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR19818:SF162; ZINC FINGER PROTEIN 728-LIKE; 1.
DR PANTHER; PTHR19818; ZINC FINGER PROTEIN ZIC AND GLI; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF02023; SCAN; 1.
DR Pfam; PF00096; zf-C2H2; 7.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 46..127
FT /note="SCAN box"
FT /evidence="ECO:0000259|PROSITE:PS50804"
FT DOMAIN 237..309
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 396..423
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 424..446
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 480..507
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 508..535
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 536..563
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 564..591
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 592..619
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 620..647
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 145..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 74383 MW; 95F119BB0D88030F CRC64;
MATALEPEDQ DLWEEEGILM VKLEDDFTCR PESVLQRDDP VLETSHQNFR RFRYQEAASP
REALIRLREL CHQWLRPERR TKEQILELLV LEQFLTVLPG ELQSWVRGQR PESGEEAVTL
VEGLQKQPRR PRRWVTVHVH GQEVLSEETV RPGAEPGSPS ELRNPVQTST PEASREETTQ
SPDLGPPEEQ SLCRELEFQP LQESEVPVSQ DADLPEERNT GNPEMVALLT ALSQGLVTFK
DVAVCFSQDQ WSDLDPAQKE FYGEYVLEED CGIVVSLSFP IPRLDEISHV REEEPLVPDI
PEPQEPQEPE ILSFTYTGDR SEDEEEYLEQ EDLCLEDLRR SILGDPEIHQ TPDWEIVFED
DPNRLSERCG TNISQVNGLS NLQESMPIHP LLGRHHDCPV CGKSFTCNSH LVRHLRTHTG
EKPYKCMECG KSYTRSSHLA RHQKVHKMGA AYKFPLNQKN LDETSPLVQA ERTPPVEKPY
RCDDCGKHFR WTSDLVRHQR THTGEKPFFC TICGKSFSQK SVLTTHQRIH LGGKPYLCGE
CGEDFSDHRR YLAHRKTHAA EELYLCSECG RCFNHSAAFA KHLRGHASVR PCRCNECGKS
FSRRDHLVRH QRTHTGEKPF TCPTCGKSFS RGYHLIRHQR THSEKTS
//
