ID   A0A384C0V5_URSMA        Unreviewed;       252 AA.
AC   A0A384C0V5;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Homeobox protein TGIF1 isoform X3 {ECO:0000313|RefSeq:XP_008688511.1};
GN   Name=TGIF1 {ECO:0000313|RefSeq:XP_008688511.1};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008688511.1};
RN   [1] {ECO:0000313|RefSeq:XP_008688511.1}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008688511.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR   RefSeq; XP_008688511.1; XM_008690289.2.
DR   AlphaFoldDB; A0A384C0V5; -.
DR   GeneID; 103662622; -.
DR   CTD; 7050; -.
DR   OrthoDB; 3180467at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   PANTHER; PTHR11850:SF59; HOMEOBOX PROTEIN TGIF1; 1.
DR   PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000313|RefSeq:XP_008688511.1};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT   DOMAIN          13..76
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        15..77
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          124..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   252 AA;  27479 MW;  12EBC420B5230BCC CRC64;
     MDIPLDLSSS ASAGKRRRRG NLPKESVQIL RDWLYEHRYN AYPSEQEKAL LSQQTHLSTL
     QVCNWFINAR RRLLPDMLRK DGKDPNQFTI SRRGAKIAEA SSVESAMGIK NFIPALEESP
     FHSCTAGPNP ALGRPLSPKP SSPGSILARP SVICHTTVTA LKDVPFSLCQ PVGVGQNTDL
     QQIAAGSFTD PSLLYPEDTC KSGPSSNPQS GLFNTPPPTP PDLNQDFSGF QLLVDVALKR
     AAEMELQAKL TA
//