ID A0A384C1Y9_URSMA Unreviewed; 378 AA.
AC A0A384C1Y9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Di-N-acetylchitobiase {ECO:0000313|RefSeq:XP_008688886.1};
GN Name=CTBS {ECO:0000313|RefSeq:XP_008688886.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008688886.1};
RN [1] {ECO:0000313|RefSeq:XP_008688886.1}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008688886.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Lysosome {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|ARBA:ARBA00009336}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_008688886.1; XM_008690664.1.
DR AlphaFoldDB; A0A384C1Y9; -.
DR STRING; 29073.ENSUMAP00000003000; -.
DR GeneID; 103662968; -.
DR KEGG; umr:103662968; -.
DR CTD; 1486; -.
DR OMA; KTYKWIM; -.
DR OrthoDB; 718898at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02875; GH18_chitobiase; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR047898; DIAC_cat.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR46290; DI-N-ACETYLCHITOBIASE; 1.
DR PANTHER; PTHR46290:SF1; DI-N-ACETYLCHITOBIASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..378
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017004562"
FT DOMAIN 1..378
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
SQ SEQUENCE 378 AA; 42830 MW; D7A492D582DFBAE3 CRC64;
MTPPQRGRLC LLARPPHGVP ALAVLLLSLL PFWAGARCPC QDPALCQPIT QHPDFEVFVF
DVGSKTWKFY DWSQITTVVI FGDYDPELMC YARSHGARVV LKGDAPLKNS TDPIFRASWI
AQKVKLAKKQ YMDGVSIDIE QEANCLSPEY YALSTLVKET TDSFHREIKG SQVTFDVTWS
PKSKDRCYNY AGIADACDFL FVMSYDERSQ ALSECIAAAN APYKETLTGY DDYIKMGINP
KKLVMGIPWY GYDYTCQNLL EDRVCTIPKV PSWRASCGIT SGRQVPYKII MKQVNSSISG
SHWDKDQQAP YYNYKDSSGH FHQVWYDNPQ SISLKAAYIQ KHGLRGIGMW HANCLDYSGD
AVAKQQTEEM WEVLKPKL
//
