ID A0A384C2V6_URSMA Unreviewed; 327 AA.
AC A0A384C2V6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Ankyrin repeat and SOCS box protein 1 isoform X2 {ECO:0000313|RefSeq:XP_008688754.1};
GN Name=ASB1 {ECO:0000313|RefSeq:XP_008688754.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008688754.1};
RN [1] {ECO:0000313|RefSeq:XP_008688754.1}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008688754.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_008688754.1; XM_008690532.2.
DR AlphaFoldDB; A0A384C2V6; -.
DR STRING; 29073.ENSUMAP00000015683; -.
DR GeneID; 103662824; -.
DR KEGG; umr:103662824; -.
DR CTD; 51665; -.
DR OrthoDB; 5475985at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03720; SOCS_ASB1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037331; ASB1_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24173:SF27; ANKYRIN REPEAT AND SOCS BOX PROTEIN 1; 1.
DR PANTHER; PTHR24173; ANKYRIN REPEAT CONTAINING; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00253; SOCS; 1.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 72..101
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 135..167
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 285..327
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 327 AA; 36471 MW; 5CF1DD2DFEA1B407 CRC64;
MVNPCMHAGP NLKEWLREQF CDHPLEHCED TRLHDAAYVG DLQTLRSLLQ EESYRSRINE
KSVWCCGWLP CTPLRIAATA GHGNCVDFLI RKGAEVDLVD VKGQTALYVA VVNGHLESAQ
ILLEAGADPN GSRHHRSTPV YHASRVGRAD ILKALIRYGA DVDVNHHLTP DIRPPFSRRL
TSLVVCPLYI SAAYHNLQCF KLLLQAGANP DFNCNGPVNT QGFYRGSPGC VMDAVLRHGC
EAAFVSLLVE FGANLNLVKW ESLGPESRGR RKVDPEALQV FKEARSVPRT LLNLCRVAVR
RALGKYRLHL IPSLPLPDPI KKFLLYE
//
