ID A0A384C819_URSMA Unreviewed; 168 AA.
AC A0A384C819;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=D-aminoacyl-tRNA deacylase {ECO:0000256|ARBA:ARBA00013056};
DE EC=3.1.1.96 {ECO:0000256|ARBA:ARBA00013056};
GN Name=LOC103664506 {ECO:0000313|Ensembl:ENSUMAP00000034370,
GN ECO:0000313|RefSeq:XP_008690619.1};
GN Synonyms=DTD2 {ECO:0000313|Ensembl:ENSUMAP00000013741,
GN ECO:0000313|RefSeq:XP_008708633.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008690619.1};
RN [1] {ECO:0000313|Ensembl:ENSUMAP00000013741}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008690619.1, ECO:0000313|RefSeq:XP_008708633.1}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008690619.1,
RC ECO:0000313|RefSeq:XP_008708633.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA +
CC H(+); Xref=Rhea:RHEA:13953, Rhea:RHEA-COMP:10123, Rhea:RHEA-
CC COMP:10124, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:59871,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:79333; EC=3.1.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00033671};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala);
CC Xref=Rhea:RHEA:53744, Rhea:RHEA-COMP:9657, Rhea:RHEA-COMP:13640,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57305,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78522; EC=3.1.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00000741};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_008690619.1; XM_008692397.2.
DR RefSeq; XP_008708633.1; XM_008710411.2.
DR STRING; 29073.ENSUMAP00000013741; -.
DR Ensembl; ENSUMAT00000016300.1; ENSUMAP00000013741.1; ENSUMAG00000010115.1.
DR Ensembl; ENSUMAT00000040651.1; ENSUMAP00000034370.1; ENSUMAG00000024717.1.
DR GeneID; 103664506; -.
DR GeneID; 103680899; -.
DR KEGG; umr:103664506; -.
DR KEGG; umr:103680899; -.
DR CTD; 112487; -.
DR OMA; GMMVYIC; -.
DR OrthoDB; 3015787at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0051499; F:D-aminoacyl-tRNA deacylase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.80.10; D-tyrosyl-tRNA(Tyr) deacylase; 1.
DR InterPro; IPR003732; Daa-tRNA_deacyls_DTD.
DR InterPro; IPR023509; DTD-like_sf.
DR PANTHER; PTHR10472:SF1; D-AMINOACYL-TRNA DEACYLASE 2; 1.
DR PANTHER; PTHR10472; D-TYROSYL-TRNA TYR DEACYLASE; 1.
DR Pfam; PF02580; Tyr_Deacylase; 1.
DR SUPFAM; SSF69500; DTD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261680}.
SQ SEQUENCE 168 AA; 18618 MW; 1BDD2A8FA5239A76 CRC64;
MAESDRIPQA RALLQQCLHA RLQVRPAEGD AESQWVEVQR GLVIYVCFFK GANKELLPKM
VNTLLNVKLS ETENGKHVSV LDLPGNVLII PQATLGGRVK GRNMQYHSNS GKEEGLELYS
QFVTLCEKEL AANSKCAEAG VVVEHGTYGN RQVLQLDTNG PYTHLIEF
//
