ID A0A384C964_URSMA Unreviewed; 1106 AA.
AC A0A384C964;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Zinc finger protein 521 isoform X2 {ECO:0000313|RefSeq:XP_008691009.2};
GN Name=ZNF521 {ECO:0000313|RefSeq:XP_008691009.2};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008691009.2};
RN [1] {ECO:0000313|RefSeq:XP_008691009.2}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008691009.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008691009.2; XM_008692787.2.
DR STRING; 29073.ENSUMAP00000029749; -.
DR KEGG; umr:103664880; -.
DR OrthoDB; 3073634at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 10.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24406; TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED; 1.
DR PANTHER; PTHR24406:SF30; ZINC FINGER PROTEIN 423; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13912; zf-C2H2_6; 5.
DR SMART; SM00355; ZnF_C2H2; 24.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 21.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 19.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 26..54
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 61..89
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 90..117
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 217..245
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 257..285
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 293..316
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 414..436
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 444..466
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 474..498
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 502..530
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 532..560
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 563..590
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 589..612
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 666..693
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 710..737
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 739..766
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 918..946
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1005..1032
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1036..1064
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 138..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 643..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 947..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1106 AA; 124679 MW; 900FDE99E1AFEEE4 CRC64;
MQVHERNKDG SQSGSRMEDW KIKDTQKCSQ CEEGFDFPED LQKHIAECHP ECSPNEDRAA
LQCIYCHELF MEETSLMNHM EQVHGGEKKN SCSICSESFH TVEELYSHMD SHQQAESCNH
SNSPSLVTVG YTSVSSTTPD SNLSVDSSTM VEAAPPIPKS RGRKRAAQQT PDMTVPSSKQ
AKVTYSCIYC NKQLFSSLAV LQIHLKTMHL DKPEQAHICQ YCLEVLPSLY NLNEHLKQVH
EAQDPGLIVS AMPAIVYQCN FCSEVVNDLN TLQEHIRCSH GFANPAAKDS NAFFCPHCYM
GFLTDSSLEE HIRQVHCDLS GSRFGSPVLG TPKEPVVEVY SCSYCTNSPI FNSVLKLNKH
IKENHKNIPL ALNYIHNGKK SRALSPLSPV AIEQTSLKMM QAVGGAPARP AGEYICNQCG
AKYTSLDSFQ THLKTHLDTV LPKLTCPQCN KEFPNQESLL KHVTIHFMIT STYYICESCD
KQFTSVDDLQ KHLLDMHTFV FFRCTLCQEV FDSKVSIQLH LAVKHSNEKK VYRCTSCNWD
FRNETDLQLH VKHNHLENQG KVHKCIFCGE SFGTEVELQC HITTHSKKYN CKFCSKAFHA
IILLEKHLRE KHCVFETKTP NCGTNGASEQ VQKEEVELQT LLTNSQESHN SHDGSEEDVD
TSEPMYGCDI CGAAYTMETL LQNHQLRDHN IRPGESAIVK KKAELIKGNY KCNVCSRTFF
SENGLREHMQ THLGPVKHYM CPICGERFPS LLTLTEHKVT HSKSLDTGNC RICKMPLQSE
EEFLEHCQMH PDLRNSLTGF RCVVCMQTVT STLELKIHGT FHMQKTGNGS AVQTTGRGQH
VQKLYKCASC LKEFRSKQDL VKLDINGLPY GLCAGCVNLS KSGSPGINIP PGTNRPGLGQ
NENLSAIEGK GKAGGLKTRC SSCNVKFESE SELQNHIQTV HRELVPESNS TQLKTPQVSP
MPRISPSQSD EKKTYQCIKC QMVFYNEWDI QVHVANHMID EGLNHECKLC SQTFDSPAKL
QCHLIEHSFE GMGGTFKCPV CFTVFVQANK LQQHIFSAHG QEDKIYDCTQ CPQKFFFQTE
LQRIYSSEQA LPCSYERNHT MTQHSS
//
