ID   A0A384CEP9_URSMA        Unreviewed;       234 AA.
AC   A0A384CEP9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=IZUMO family member 3 {ECO:0000313|Ensembl:ENSUMAP00000007414};
DE   SubName: Full=Izumo sperm-egg fusion protein 3 isoform X2 {ECO:0000313|RefSeq:XP_008693297.1};
GN   Name=IZUMO3 {ECO:0000313|Ensembl:ENSUMAP00000007414,
GN   ECO:0000313|RefSeq:XP_008693297.1};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008693297.1};
RN   [1] {ECO:0000313|Ensembl:ENSUMAP00000007414}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2019) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_008693297.1}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008693297.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Izumo family.
CC       {ECO:0000256|ARBA:ARBA00009633}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_008693297.1; XM_008695075.1.
DR   STRING; 29073.ENSUMAP00000007411; -.
DR   Ensembl; ENSUMAT00000008891.1; ENSUMAP00000007414.1; ENSUMAG00000005720.1.
DR   GeneID; 103666994; -.
DR   KEGG; umr:103666994; -.
DR   CTD; 100129669; -.
DR   OrthoDB; 5259216at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR029389; IZUMO.
DR   PANTHER; PTHR36470; IZUMO SPERM-EGG FUSION PROTEIN 3; 1.
DR   PANTHER; PTHR36470:SF1; IZUMO SPERM-EGG FUSION PROTEIN 3; 1.
DR   Pfam; PF15005; IZUMO; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..234
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5041072280"
FT   TRANSMEM        171..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   234 AA;  27399 MW;  D8BBA566F29137B4 CRC64;
     MGDLWLLLLL PLSLADFHGV KGCLECDPKF TEDIRSLLAK LIPSEVPGRV HLLERQIKEM
     IRLSFKVSHR DKMLRVLAVH KVIKLRIWLK NELYKLGNET WKGAFILQGK LLDVRQNLES
     KLKEILKNFS EVVVTEGPIL DCWTCLRITS RCFRGEYCGE EDSKKVESRE IALFLILLTE
     VVMLGSALLL FHICVSHRRK MKAIRKSLKK YLEKKLEELM ERTDEKEKHD FEIR
//