ID   A0A384CHQ6_URSMA        Unreviewed;       471 AA.
AC   A0A384CHQ6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177};
DE            EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};
GN   Name=FMO4 {ECO:0000313|RefSeq:XP_008694401.1};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008694401.1};
RN   [1] {ECO:0000313|RefSeq:XP_008694401.1}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008694401.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|RuleBase:RU361177};
CC   -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183,
CC       ECO:0000256|RuleBase:RU361177}.
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DR   RefSeq; XP_008694401.1; XM_008696179.2.
DR   AlphaFoldDB; A0A384CHQ6; -.
DR   GeneID; 103667879; -.
DR   CTD; 2329; -.
DR   OrthoDB; 2079054at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000960; Flavin_mOase.
DR   InterPro; IPR020946; Flavin_mOase-like.
DR   InterPro; IPR002256; Flavin_mOase_4.
DR   PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR   PANTHER; PTHR23023:SF74; DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 4; 1.
DR   Pfam; PF00743; FMO-like; 1.
DR   PRINTS; PR00370; FMOXYGENASE.
DR   PRINTS; PR01124; FMOXYGENASE4.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|RuleBase:RU361177};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW   ECO:0000256|RuleBase:RU361177};
KW   Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW   ECO:0000256|RuleBase:RU361177}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU361177};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680}.
SQ   SEQUENCE   471 AA;  52978 MW;  939253DD60D643BF CRC64;
     MARRVAVIGA GVSGLSSIKC CLDEGLEPIC FERSNNFGGL WKFTESSEDG MNRIYRSLVT
     NTCKEMSCYS DFPFQEDYPN FMNQEKFWNY LQEFAEHFDL LKYIRFRVLL STRTGAWVLC
     RSSDGGYPFN MVITRRCINF IAQVLPSCVL NRIQERQLNK RFNHENYGLS ITKGKKSKFV
     VNDELPTCIL CGTITMKTSV KEFTETSALF EDGTVGENID IVIFATGYTF SFPFFEEPFK
     SLCTKKIFLY KRVFPSNLER ATLAVIGFIG LKGSILAATE LQARWATRVF KGLCQIPPSQ
     KLMAEATKKE QLIKRPHVSK YCQRPSSNKS RIQTLPATPP ATPDQATVIS HQDTCWHPLL
     WSPCFQSDLD TAAGLSNSTL LFCSKPSDCF PFHSQKLPCS SASLQSNQLA LCPHCLLSSH
     FTHTAPVTPA SSPVHKHANH SPSEPLHLLF LLPGMFSPPD IYRLSLSNIT S
//