ID A0A384CJ31_URSMA Unreviewed; 1051 AA.
AC A0A384CJ31;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Rab GTPase-activating protein 1-like isoform X1 {ECO:0000313|RefSeq:XP_008694817.2};
GN Name=RABGAP1L {ECO:0000313|RefSeq:XP_008694817.2};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008694817.2};
RN [1] {ECO:0000313|RefSeq:XP_008694817.2}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008694817.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008694817.2; XM_008696595.2.
DR STRING; 29073.ENSUMAP00000027766; -.
DR KEGG; umr:103668381; -.
DR Proteomes; UP000261680; Unplaced.
DR CDD; cd01211; PTB_Rab6GAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR PANTHER; PTHR47219:SF7; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT DOMAIN 136..251
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 538..724
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 807..912
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 965..1020
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 119442 MW; 8834B2FF9873CB36 CRC64;
MEVRASLQKV SGSSDSVATL NSEEFVLVPQ HADDTSTKDD EKPELKIVSN GDEQLEKAME
EILRDSEKGQ SSLLVDCQSP TEISDHSFGD VSASQTNKPS LQLILDPSNT EISTPRPSSP
SGLPEEDSVL FNKLTYLGCM KVSSPRNEVE ALRAMATMKS SSQHPFPVTL YVPNVPEGSV
RIIDQSNNVE LASFPIYKVL FCARGHDGTT ESNCFAFTES SHGSEEFQIH VFSCEIKEAV
SRILYSFCTA FKRSSRQVSD VKDSVIPTPD SDVFTFSVSL EVKEDDGKGN FSPVPKDRDK
FYFKLKQGIE KKVVITVQQL SNKELAIERC FGMLLSPGRN VKNSDMHLLD MESMGKSYDG
RAYVITGMWN PNVPIFLALN EETPKDKRVY MTVAVDMVVT EVVEPVRFLL ETVVRVYPAN
ERFWYFSRKT FTETFFMRLK QSEGKGHTNA GDAIYEVVSL QRQSEKEEPV TPTSGGGPVS
PQEDEAEEES DNELSSGTGD VSKDCPEKIL YSWGELLGRW HSNLGARPKG LSTLVKSGVP
EALRAEVWQL LAGCHDNQAM LDRYRLLITK DSAQESVITR DIHRTFPAHD YFKDTGGDGQ
ESLYKICKAY SVYDEDIGYC QGQSFLAAVL LLHMPEEQAF CVLVKIMYDY GLRDLYKNNF
EDLHCKFYQL ERLIQEQLPD LHHHFCVLKL EVHMYASQWF LTLFTAKFPL CMVFHIIDLL
LCEGLNIIFH VALALLKTSK EDLLQADFEG ALKFFRVQLP KRYRAEENAR RLMEQACNIK
VPTKKLKKYE KEYQTMRESQ LQQEDPMDRY KRENRRLQEA SMRLEQENDD LAHELVTSKI
ALRNDLDQAE DKADVLNKEL LLTKQRLVET EEEKRKQEEE TAQLKEVFRK QLEKAEYEIK
KTTAIIAEYK QICSQLSTRL ETQQAASKEE LEVVKGKMMA CKHCSDIFSK EGALKPVAVS
REEPGVDLDD EKDSLKKQLR EMELELAQTK LQLVEAKCKI QELEHQRGAL MNEIQAAKNS
WFSKTLNSIK TATGTQPLQP PLATQPPKES T
//
