ID A0A384CTF9_URSMA Unreviewed; 188 AA.
AC A0A384CTF9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=COMM domain-containing protein 1 {ECO:0000256|ARBA:ARBA00016551};
GN Name=COMMD1 {ECO:0000313|Ensembl:ENSUMAP00000028811,
GN ECO:0000313|RefSeq:XP_008698132.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008698132.1};
RN [1] {ECO:0000313|Ensembl:ENSUMAP00000028811}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_008698132.1}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008698132.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_008698132.1; XM_008699910.2.
DR STRING; 29073.ENSUMAP00000028811; -.
DR Ensembl; ENSUMAT00000034070.1; ENSUMAP00000028811.1; ENSUMAG00000020922.1.
DR GeneID; 103671306; -.
DR KEGG; umr:103671306; -.
DR CTD; 150684; -.
DR OMA; WRIDGKS; -.
DR OrthoDB; 6795at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005769; C:early endosome; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0055037; C:recycling endosome; IEA:Ensembl.
DR GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Ensembl.
DR GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0019871; F:sodium channel inhibitor activity; IEA:Ensembl.
DR GO; GO:0055070; P:copper ion homeostasis; IEA:Ensembl.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:Ensembl.
DR GO; GO:2000009; P:negative regulation of protein localization to cell surface; IEA:Ensembl.
DR GO; GO:1902306; P:negative regulation of sodium ion transmembrane transport; IEA:Ensembl.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:Ensembl.
DR GO; GO:0048227; P:plasma membrane to endosome transport; IEA:Ensembl.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd04749; Commd1_MURR1; 1.
DR InterPro; IPR017920; COMM.
DR InterPro; IPR033776; COMMD1_N.
DR InterPro; IPR037351; Murr1.
DR PANTHER; PTHR21199; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21199:SF1; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF07258; COMM_domain; 1.
DR Pfam; PF17221; COMMD1_N; 1.
DR PROSITE; PS51269; COMM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT DOMAIN 117..185
FT /note="COMM"
FT /evidence="ECO:0000259|PROSITE:PS51269"
SQ SEQUENCE 188 AA; 20939 MW; FA045375ACB34EC1 CRC64;
MAGELEGSKS LSGLLSGLAQ EAFHGHQGIT EELLRSQLYP EVSLEEFRPF LAKMRGILKS
IASADMDFNQ LEAFLTAQTK KQGGITSDQA AVISKFWKSH KTKIRESLMN QSRWDSGLRG
LSWRVDGKSQ SRHSAQIHTP VAIMELEIGK SGQESEFLCL EFDEVKVNQL LKKLSEVEES
ISTLMQPA
//
