ID A0A384CY07_URSMA Unreviewed; 3100 AA.
AC A0A384CY07;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 10-FEB-2021, entry version 11.
DE SubName: Full=LOW QUALITY PROTEIN: centromere protein F {ECO:0000313|RefSeq:XP_008699370.1};
GN Name=CENPF {ECO:0000313|RefSeq:XP_008699370.1};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008699370.1};
RN [1] {ECO:0000313|RefSeq:XP_008699370.1}
RP IDENTIFICATION.
RC TISSUE=Muscle sample {ECO:0000313|RefSeq:XP_008699370.1};
RG RefSeq;
RL Submitted (OCT-2020) to UniProtKB.
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DR RefSeq; XP_008699370.1; XM_008701148.1.
DR GeneID; 103672451; -.
DR KEGG; umr:103672451; -.
DR CTD; 1063; -.
DR Proteomes; UP000261680; Genome assembly.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 3.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT DOMAIN 1..307
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1882..2022
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2118..2257
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2300..2439
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2956..2999
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 246..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2886..3100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 13..131
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 164..191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 386..413
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 418..438
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 463..487
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 509..615
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 623..643
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 651..671
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 686..713
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 725..759
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 839..866
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 899..947
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 955..996
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1029..1077
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1118..1159
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1202..1243
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1293..1320
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1332..1359
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1397..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1550..1613
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1779..1848
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1879..1899
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1921..1948
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1956..1986
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2003..2072
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2129..2163
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2171..2191
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2199..2258
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2276..2303
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2311..2447
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2476..2590
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2598..2664
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2669..2703
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2740..2812
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2820..2850
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2858..2878
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2902..2918
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2941..2970
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3010..3066
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3100 AA; 355980 MW; 1EB58442C198D556 CRC64;
MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
CKSELERSQQ AAQAADVSVY SSSTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPTRLSL NALKTPIRRD
FSASHFSGEQ EVTPSRSTLQ TGKRDANSSF CDNSSNSHLL DQLKAQNQEL RNKISDLELH
LQGQEKEMKG QANKCQELQL QLEKAKAELI EKEKALNKSR DELVRSTAQY DQASAKCTAL
EQKLKRLSED LSCQRQNAES ARCSLEQKLK EKEKEFQEEL SRQQRTFQAL DQESTQMKAR
LTQELQQAKN THNILQADLD KVTSGKYQLE KTLEEFKQKF CRAEQALQAS QVKENELRRS
SEEAKKEYSL LKGQSEQRAR EVCHLEEELR KAKQSLSQSQ NVAEEMRAKN ASQETMLRDL
QEKVNQQENS LTLDKLKLAL VDLEKQRDCS QDLLKKREHH IEQLNDKLSK MEKESEALLI
ALELKKKEYE ELKEEKTLFA RWKSENEQLL SQLESEKGSL QSKINHLETC LKTQQIKSHE
YNEKVRTLEM ESENLHVEIR NLHNMIDSKT VEVETQKQAY ADLQQKAEFS DQKHKKETEN
MCLKISELTG QVEDLEHKLQ LLSSEVIDKD QRYQDLQAEY ESLGDLLKSK DSSLVTNETH
HRSLLAFEQQ SAMNNSFVNI IGEQGSTPSE RSKCHLEALP SPKSSAILQN RVLSLEFSLE
SQKQMNSDLQ KQCEELVQIR GEIEENLIKA EQMHQSFVAE TSQRISKLQE DTSVHQNAFA
ETLVALENKE REIQLLNEKL ETEQAEIQEL KKSNHLLQES LKALQLLSET LSSEKKEMSS
TISLNRKEIE DLTQENETLK EINATLNQEK INLLQKSESF SNCIDERDKS ISELSNQYKQ
ERLILQQRCE ETGRAFEDLS EKYQAAQEKN SQLECLLNEC TSACENRQKE LDHLKETFAR
EQEVFVTKLA LAEETNQNLV LELGAVQQDL RSEIADIQNN SKSEADGLKQ EIMTLKEEHS
KMQKELNALM QENEHLMMLM ETKQEHQILE SEAISDSVEG ESEINKCHVQ LPMDLEVKDP
SLDCYNAQLM QLEAKRRNRE LKLQESEKDK ECLQHELQTI GIELETGNLQ RDAQSQELSG
PKDCDIGTEE KYISVLHELS ASQNDNALLQ CSLQTAMSKL SELEKMCEML QVEKLELMSE
LNDSRSECIT TTSKMAEEME KLVNEVKILN DENDLLQGEL VKDMVEGESD ERQNEQKRAS
FNPLDDSNCY EHLTLSNKEV QMHFAELQEK FSSLQSEHKV LYDQHRQVSS KMSELQSYVD
TLKAENSILS TSLRNFQGDL VKEEMLGPED GHFLSLSFSC VTDSPSLTRL GESSFCKDLL
DQTGETSLLN NLEGTISANQ SNIEEGSCCS PGEEKNLTRK EILSAPARSV EELETLCQMY
LDSLKKLEDK IESQEIMKSK EIKELEQLLS SEREELDCLR KQYLSENEQW QQKLTSVTME
MESKLAAEKK QTEHLSFELE VARLQLQGLD LSSRSLLGPD IEEALQVGNN SCDVKESEEH
TLETKERTPK HDIHQXLGME KVTKTSPVRF TEEWSREQSL ETPAEDKTEG CLERISDLSF
SGPNALVPMD FLETQVTIQN LQLQVKESSN ENLRLLHIIE ERDKKVESLL NEIKELDSKL
HVQKAQITAK MEACIELEKM VEELKKEKSN LSERLESFSC DKQELHQRTE SLEGLNSSLE
ICADKLSHAI IEDSVAKVND NWRERFLDVE NELKRIQSEK GSIEHHALSL EADLETVQTE
KLYLEKDNEN QQNIIIRLEE ELSVVTSERN RLHGELDTLS KENKELDLMS EKMKQKIREL
ESHQGEGHID VAGAEVRDQT QLIETLSSDV TKLLEENTHL QEQLQNMEKD SQALSLVKSE
LEIQIEQLSR EKESLARESE SLQTRLHESE HEKLTVTKAL EGALLEKGEV AVRLSSTQEE
VYQLRQGIEK LRVRIEADDK KQLHVLEKLR ASERKADSLQ DKVENLEREL QMSEENQELV
ILDAETSKAE VEALKTQMEL MTKSLGDLEL DLGTIRFEKE NLVKQLQEKQ GQVSELDTLL
SSLKGRLEEE EQEKIEMREE SKAALEMLQT QLKELNEEVI ALCHGQEIQK VEEQSLDHSV
QEIHQLRNSI EKLKVRLEAD EKEQLQVLGK LTESEHHVDL LKDRVENLER ELERSRENQE
RVILEAENSK AEVGTLKAKI EEMAQTLRDL KLDLVHIRSE KENVIKELQK EQGRVSELEI
LNSSFENLLQ EKEQEKVQMK EESKIAVETL QTQLKELNEK VAALCHDQDT WKAQAQSLHS
QVDALGYEKA QLLQGLDEVK NNYLNVQSSA NSLLQQVEDG KQKLEKKDEE ISILKNQVQD
REQLASKLSQ VEGEQQLWKK QKVELENLMV ELEEKIRVLQ SKNDTLQDTL EALQDSHRDL
EKELELTKME NVSFVEKVNA MTGKETELQR EMREMAQKTT ELKEEYFGEK NRLTEELNIM
SQEIKSSKGQ LEELMLENSE LKKSLDYIHK DQMEKEEKVQ EERAEYQLQL QEAEKKHQAL
LLDTNKQYEM EIQTYREKLS SREECLSLQK AEVDLLKSSK EELNNSLKAT TQILEELKKT
KADNVKYTNQ LKKENERAQG KIKLLIKSCK QLEEEKEMLQ KELSHLEAAQ EKQKTGTVVD
SNVEDLMAEI KELKETLEEK NKEADEYLDK YCSLLISHEK LEKAKEMLET QVARLSSQSK
LNLQHSPLLN SVVPEASPAP SATEKKLSSS QNKASGKRQR STGIREDGGG TAPSTPETFS
KKSRKAVKSG IHPAEDARDT EFEPEGLPEV VKKGFADIPT GKASPYVLRR TTMPTRTSPR
LAAQKLAPSP LSLNKENHAE TSQPTAGGSR SQKVKVAQQS PADSSAPFRE PTTRSLSVSN
LPERSPANSP REGLRAKRGR LAPSPEAVPE SKSSENCRVQ
//
