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Database: UniProt
Entry: A0A384CY07_URSMA
LinkDB: A0A384CY07_URSMA
Original site: A0A384CY07_URSMA 
ID   A0A384CY07_URSMA        Unreviewed;      3100 AA.
AC   A0A384CY07;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   10-FEB-2021, entry version 11.
DE   SubName: Full=LOW QUALITY PROTEIN: centromere protein F {ECO:0000313|RefSeq:XP_008699370.1};
GN   Name=CENPF {ECO:0000313|RefSeq:XP_008699370.1};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008699370.1};
RN   [1] {ECO:0000313|RefSeq:XP_008699370.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle sample {ECO:0000313|RefSeq:XP_008699370.1};
RG   RefSeq;
RL   Submitted (OCT-2020) to UniProtKB.
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DR   RefSeq; XP_008699370.1; XM_008701148.1.
DR   GeneID; 103672451; -.
DR   KEGG; umr:103672451; -.
DR   CTD; 1063; -.
DR   Proteomes; UP000261680; Genome assembly.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT   DOMAIN          1..307
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1882..2022
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2118..2257
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2300..2439
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2956..2999
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          246..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2886..3100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          386..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          418..438
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          463..487
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          509..615
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          623..643
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          651..671
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          686..713
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          725..759
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          839..866
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          899..947
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          955..996
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1029..1077
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1118..1159
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1202..1243
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1293..1320
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1332..1359
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1397..1417
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1550..1613
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1779..1848
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1879..1899
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1921..1948
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1956..1986
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2003..2072
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2129..2163
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2171..2191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2199..2258
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2276..2303
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2311..2447
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2476..2590
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2598..2664
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2669..2703
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2740..2812
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2820..2850
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2858..2878
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        2902..2918
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2941..2970
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        3010..3066
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   3100 AA;  355980 MW;  1EB58442C198D556 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKERQQRQFQ LETLEAALQK QKQKVENEKT
     EGANLKRENQ SLMEICENLE KTKQKISHEL QVKESQVNFQ EGQLNSSKKQ IEKLEQELKR
     CKSELERSQQ AAQAADVSVY SSSTPQKIFA TPLTPSQYYS GSKYEDLKEK YNKEVEERKR
     LEAEVKALQA KKASQAIPQS TMNHRDIARH QASSSVFSWQ QEKTPTRLSL NALKTPIRRD
     FSASHFSGEQ EVTPSRSTLQ TGKRDANSSF CDNSSNSHLL DQLKAQNQEL RNKISDLELH
     LQGQEKEMKG QANKCQELQL QLEKAKAELI EKEKALNKSR DELVRSTAQY DQASAKCTAL
     EQKLKRLSED LSCQRQNAES ARCSLEQKLK EKEKEFQEEL SRQQRTFQAL DQESTQMKAR
     LTQELQQAKN THNILQADLD KVTSGKYQLE KTLEEFKQKF CRAEQALQAS QVKENELRRS
     SEEAKKEYSL LKGQSEQRAR EVCHLEEELR KAKQSLSQSQ NVAEEMRAKN ASQETMLRDL
     QEKVNQQENS LTLDKLKLAL VDLEKQRDCS QDLLKKREHH IEQLNDKLSK MEKESEALLI
     ALELKKKEYE ELKEEKTLFA RWKSENEQLL SQLESEKGSL QSKINHLETC LKTQQIKSHE
     YNEKVRTLEM ESENLHVEIR NLHNMIDSKT VEVETQKQAY ADLQQKAEFS DQKHKKETEN
     MCLKISELTG QVEDLEHKLQ LLSSEVIDKD QRYQDLQAEY ESLGDLLKSK DSSLVTNETH
     HRSLLAFEQQ SAMNNSFVNI IGEQGSTPSE RSKCHLEALP SPKSSAILQN RVLSLEFSLE
     SQKQMNSDLQ KQCEELVQIR GEIEENLIKA EQMHQSFVAE TSQRISKLQE DTSVHQNAFA
     ETLVALENKE REIQLLNEKL ETEQAEIQEL KKSNHLLQES LKALQLLSET LSSEKKEMSS
     TISLNRKEIE DLTQENETLK EINATLNQEK INLLQKSESF SNCIDERDKS ISELSNQYKQ
     ERLILQQRCE ETGRAFEDLS EKYQAAQEKN SQLECLLNEC TSACENRQKE LDHLKETFAR
     EQEVFVTKLA LAEETNQNLV LELGAVQQDL RSEIADIQNN SKSEADGLKQ EIMTLKEEHS
     KMQKELNALM QENEHLMMLM ETKQEHQILE SEAISDSVEG ESEINKCHVQ LPMDLEVKDP
     SLDCYNAQLM QLEAKRRNRE LKLQESEKDK ECLQHELQTI GIELETGNLQ RDAQSQELSG
     PKDCDIGTEE KYISVLHELS ASQNDNALLQ CSLQTAMSKL SELEKMCEML QVEKLELMSE
     LNDSRSECIT TTSKMAEEME KLVNEVKILN DENDLLQGEL VKDMVEGESD ERQNEQKRAS
     FNPLDDSNCY EHLTLSNKEV QMHFAELQEK FSSLQSEHKV LYDQHRQVSS KMSELQSYVD
     TLKAENSILS TSLRNFQGDL VKEEMLGPED GHFLSLSFSC VTDSPSLTRL GESSFCKDLL
     DQTGETSLLN NLEGTISANQ SNIEEGSCCS PGEEKNLTRK EILSAPARSV EELETLCQMY
     LDSLKKLEDK IESQEIMKSK EIKELEQLLS SEREELDCLR KQYLSENEQW QQKLTSVTME
     MESKLAAEKK QTEHLSFELE VARLQLQGLD LSSRSLLGPD IEEALQVGNN SCDVKESEEH
     TLETKERTPK HDIHQXLGME KVTKTSPVRF TEEWSREQSL ETPAEDKTEG CLERISDLSF
     SGPNALVPMD FLETQVTIQN LQLQVKESSN ENLRLLHIIE ERDKKVESLL NEIKELDSKL
     HVQKAQITAK MEACIELEKM VEELKKEKSN LSERLESFSC DKQELHQRTE SLEGLNSSLE
     ICADKLSHAI IEDSVAKVND NWRERFLDVE NELKRIQSEK GSIEHHALSL EADLETVQTE
     KLYLEKDNEN QQNIIIRLEE ELSVVTSERN RLHGELDTLS KENKELDLMS EKMKQKIREL
     ESHQGEGHID VAGAEVRDQT QLIETLSSDV TKLLEENTHL QEQLQNMEKD SQALSLVKSE
     LEIQIEQLSR EKESLARESE SLQTRLHESE HEKLTVTKAL EGALLEKGEV AVRLSSTQEE
     VYQLRQGIEK LRVRIEADDK KQLHVLEKLR ASERKADSLQ DKVENLEREL QMSEENQELV
     ILDAETSKAE VEALKTQMEL MTKSLGDLEL DLGTIRFEKE NLVKQLQEKQ GQVSELDTLL
     SSLKGRLEEE EQEKIEMREE SKAALEMLQT QLKELNEEVI ALCHGQEIQK VEEQSLDHSV
     QEIHQLRNSI EKLKVRLEAD EKEQLQVLGK LTESEHHVDL LKDRVENLER ELERSRENQE
     RVILEAENSK AEVGTLKAKI EEMAQTLRDL KLDLVHIRSE KENVIKELQK EQGRVSELEI
     LNSSFENLLQ EKEQEKVQMK EESKIAVETL QTQLKELNEK VAALCHDQDT WKAQAQSLHS
     QVDALGYEKA QLLQGLDEVK NNYLNVQSSA NSLLQQVEDG KQKLEKKDEE ISILKNQVQD
     REQLASKLSQ VEGEQQLWKK QKVELENLMV ELEEKIRVLQ SKNDTLQDTL EALQDSHRDL
     EKELELTKME NVSFVEKVNA MTGKETELQR EMREMAQKTT ELKEEYFGEK NRLTEELNIM
     SQEIKSSKGQ LEELMLENSE LKKSLDYIHK DQMEKEEKVQ EERAEYQLQL QEAEKKHQAL
     LLDTNKQYEM EIQTYREKLS SREECLSLQK AEVDLLKSSK EELNNSLKAT TQILEELKKT
     KADNVKYTNQ LKKENERAQG KIKLLIKSCK QLEEEKEMLQ KELSHLEAAQ EKQKTGTVVD
     SNVEDLMAEI KELKETLEEK NKEADEYLDK YCSLLISHEK LEKAKEMLET QVARLSSQSK
     LNLQHSPLLN SVVPEASPAP SATEKKLSSS QNKASGKRQR STGIREDGGG TAPSTPETFS
     KKSRKAVKSG IHPAEDARDT EFEPEGLPEV VKKGFADIPT GKASPYVLRR TTMPTRTSPR
     LAAQKLAPSP LSLNKENHAE TSQPTAGGSR SQKVKVAQQS PADSSAPFRE PTTRSLSVSN
     LPERSPANSP REGLRAKRGR LAPSPEAVPE SKSSENCRVQ
//
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