ID   A0A384CZ84_URSMA        Unreviewed;       535 AA.
AC   A0A384CZ84;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   03-AUG-2022, sequence version 2.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Lebercilin-like protein {ECO:0000256|ARBA:ARBA00041189};
DE   AltName: Full=Leber congenital amaurosis 5-like protein {ECO:0000256|ARBA:ARBA00041402};
GN   Name=LCA5L {ECO:0000313|RefSeq:XP_008700142.2};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008700142.2};
RN   [1] {ECO:0000313|RefSeq:XP_008700142.2}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008700142.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LCA5 family.
CC       {ECO:0000256|ARBA:ARBA00010229}.
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DR   RefSeq; XP_008700142.2; XM_008701920.2.
DR   AlphaFoldDB; A0A384CZ84; -.
DR   STRING; 29073.ENSUMAP00000002019; -.
DR   KEGG; umr:103673170; -.
DR   OrthoDB; 5359778at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   InterPro; IPR026188; Lebercilin-like.
DR   InterPro; IPR028933; Lebercilin_dom.
DR   PANTHER; PTHR16650; C21ORF13-RELATED; 1.
DR   PANTHER; PTHR16650:SF9; LEBERCILIN-LIKE PROTEIN; 1.
DR   Pfam; PF15619; Lebercilin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT   DOMAIN          9..201
FT                   /note="Lebercilin"
FT                   /evidence="ECO:0000259|Pfam:PF15619"
FT   REGION          239..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          402..535
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          70..128
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        239..263
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        287..370
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        449..484
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..523
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  60708 MW;  E37A97E121B74C37 CRC64;
     MITQRRDAMT HRLLSARLHK IKELKNELGD IHRRLEATVI ENQFLKHLQF KHLKALGKYE
     SSQNNLPQIT AKHQNEVKNL RQLLRKSQEK ERSASRKLRE ADSELLRTKD ALQVLQKLSE
     DKNLAEREEL TQRLSVLTTK TEANDKKIQS LEKQLRLNNR AFNRQLAIET RKTLAAQAST
     KTLQMEIKRL QQKLKEKDRE LEIRNIYTSR ILKNLHDKED YPKVSSTKSV QADRSFSLTS
     MKHQETQKSE ATPSVTAQGE RTTRNIGPKE ESAAITRAIP HCGSELPNQE DSKRKHEDLS
     EEEEHLEVQP PLENTGRKRE TKEDQEKKAT SVKEELPPKR IQVTHPEREG KQEDDAGKEK
     FKRSLQINDT EEMPDKNAAS NIKIPFRQRK HYSFTEAIEN LHHGLPASGG PVSAGVTRGG
     AATSKPRGNA EGLKPEHSVS GYEPSFGKSS RTKAKDTFRD KKSSLMEELF GSGHVFKHDR
     TRPAAQRAQP TPESKTHRRA PSQASASNAL GDSNGTVVNS IKSPSPAEGK RKIII
//