ID A0A384D6V3_URSMA Unreviewed; 295 AA.
AC A0A384D6V3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=EGF like domain multiple 7 {ECO:0000313|Ensembl:ENSUMAP00000032122};
GN Name=EGFL7 {ECO:0000313|Ensembl:ENSUMAP00000032122};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Ensembl:ENSUMAP00000032122};
RN [1] {ECO:0000313|Ensembl:ENSUMAP00000032122}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_008702490.1; XM_008704268.1.
DR AlphaFoldDB; A0A384D6V3; -.
DR Ensembl; ENSUMAT00000037973.1; ENSUMAP00000032117.1; ENSUMAG00000023151.1.
DR Ensembl; ENSUMAT00000037979.1; ENSUMAP00000032122.1; ENSUMAG00000023151.1.
DR OrthoDB; 5388104at2759; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR011489; EMI_domain.
DR PANTHER; PTHR14949; EGF-LIKE-DOMAIN, MULTIPLE 7, 8; 1.
DR PANTHER; PTHR14949:SF21; EPIDERMAL GROWTH FACTOR-LIKE PROTEIN 7; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF07546; EMI; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..40
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 41..295
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036073068"
FT DOMAIN 48..125
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 124..156
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 195..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 128..138
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 146..155
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 295 AA; 32164 MW; 6078E612CF8C8EB1 CRC64;
MASLSLGAPL RRRPPHLQTR AMFNSRELLL LCFLVPAVGG TEHIFRPGRR VCATGAPRGP
ESESFVQRVY QPFLTTCDGH RACSTYRTIY RTAYRRSPGL AAPRPRYACC PGWKRTSGLP
RACGAAVCQP PCQNGGSCVQ PGRCHCPAGW QGDTCQTDVD ECRAGGGTCP QHCVNTAGSY
WCQCREGHGP SAEGVPCLPE RGTPRVAPNP TTGTDSAVEE EVRRLRSRVD VLEQKLQLVL
APLHSLALRA LEHGLPDPSS LLAHSFRQLD RIDSLSEQIS FLEEQQGSCS CKKEL
//
