ID A0A384D7T5_URSMA Unreviewed; 517 AA.
AC A0A384D7T5;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 03-AUG-2022, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Keratin, type II cuticular Hb2 {ECO:0000313|RefSeq:XP_008702830.2};
GN Name=KRT82 {ECO:0000313|RefSeq:XP_008702830.2};
OS Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008702830.2};
RN [1] {ECO:0000313|RefSeq:XP_008702830.2}
RP IDENTIFICATION.
RC TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008702830.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_008702830.2; XM_008704608.2.
DR AlphaFoldDB; A0A384D7T5; -.
DR STRING; 29073.ENSUMAP00000012151; -.
DR KEGG; umr:103675508; -.
DR OrthoDB; 4640531at2759; -.
DR Proteomes; UP000261680; Unplaced.
DR GO; GO:0045095; C:keratin filament; IEA:Ensembl.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF12; KERATIN, TYPE II CUTICULAR HB2; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT COILED 171..205
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 327..407
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 517 AA; 56942 MW; 6581F99A98E413CD CRC64;
MSCRSFQLGS RCGGRNFSSC SAVLPRMVTQ YAVSRGPCRP GGGGALRALG CLGSRSLCNM
GFGRPRVASR CGLPSFGYRV GAPCGPSACI APVTINESLL VPLQLEIDPA VQRVKRDEKE
QIKCLNNRFA SFINKVRFLE QKNKLLETKW NFMQQQKCCQ NNIEPIFETY ISTLRRQLDC
VAGDRARLEA ELGSLQDALE SYKKKYEEEL SLRPCAENEF VALKKDVDTA FLMKADLETN
AEALVQEIDF LKSLYEEEIC LLQSQISETS VIVKMDNSRE LDVDGIIAEI KAQYDDIASR
SKAEAEAWYQ SRYEELRLTA GSHCDNLRNR KNEILEMNKL IQRLQQEIEN TKAQRCKLEA
AVTQAEQQGE AALSDAKCKL AGLEEALQKA KQDMACLLKE YQEVMNSKLG LDIEIATYRR
LLEGEEHRLC EGIGPVNISV SSSKGAVLYE PCVVSTPVLR TEYCPGGTSV LKTSGGCSVV
GTGEVYIPCE PQGLLGCVSG RGASVKLGAG SSSSHKC
//
