ID   A0A384DLQ2_URSMA        Unreviewed;       234 AA.
AC   A0A384DLQ2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   03-AUG-2022, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=TIR domain-containing adapter molecule 2-like {ECO:0000313|RefSeq:XP_008707699.2};
GN   Name=LOC103679954 {ECO:0000313|RefSeq:XP_008707699.2};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008707699.2};
RN   [1] {ECO:0000313|RefSeq:XP_008707699.2}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008707699.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_008707699.2; XM_008709477.2.
DR   KEGG; umr:103679954; -.
DR   OrthoDB; 5315700at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR046946; TCAM1/2.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR47230; TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1; 1.
DR   PANTHER; PTHR47230:SF2; TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680}.
FT   DOMAIN          72..234
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   234 AA;  26494 MW;  4495DE7274738D65 CRC64;
     MGVGKSKIDP CPLSLSWGKS PGVEMSQRRQ ESASKKPDDL PLSDLAEPSP KALAPTGEGE
     GAEDRGDTSE EEEDEVFLKF VILHAEDDTD EALRVQNVLQ NDFGIKPGIV FAEMPCGRQH
     LQNLDDAVNG SAWTILLLTE NFLRDTWCKF QFYTSLMNSV NRQHKYNSVI PMRPLNNPLP
     RERTPFALRT INALEEESRG FPTQVERIFQ ESVYQIQQSL WKETKSSVRR QVIS
//