ID   A0A384DNY7_URSMA        Unreviewed;       398 AA.
AC   A0A384DNY7;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Interferon regulatory factor 2 {ECO:0000313|Ensembl:ENSUMAP00000018746};
GN   Name=IRF2 {ECO:0000313|Ensembl:ENSUMAP00000018746};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Ensembl:ENSUMAP00000018746};
RN   [1] {ECO:0000313|Ensembl:ENSUMAP00000018746}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   RefSeq; XP_008708713.1; XM_008710491.1.
DR   AlphaFoldDB; A0A384DNY7; -.
DR   STRING; 29073.ENSUMAP00000018746; -.
DR   Ensembl; ENSUMAT00000022172.1; ENSUMAP00000018746.1; ENSUMAG00000013766.1.
DR   OrthoDB; 3740806at2759; -.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005925; C:focal adhesion; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   CDD; cd00103; IRF; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR019817; Interferon_reg_fac_CS.
DR   InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR   InterPro; IPR017431; IRF1/IRF2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR   PANTHER; PTHR11949:SF22; INTERFERON REGULATORY FACTOR 2; 1.
DR   Pfam; PF00605; IRF; 1.
DR   PIRSF; PIRSF038196; IFN_RF1/2; 1.
DR   PRINTS; PR00267; INTFRNREGFCT.
DR   SMART; SM00348; IRF; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00601; IRF_1; 1.
DR   PROSITE; PS51507; IRF_2; 1.
PE   4: Predicted;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
SQ   SEQUENCE   398 AA;  44700 MW;  CD346BBF39C686B5 CRC64;
     MTVGSPTYGK AVMYFGVFRA HMWRPEVSFG GNDAAQVTIR GPITLFQGTM PVERMRMRPW
     LEEQINSNTI PGLKWLNKEK KIFQIPWMHA ARHGWDVEKD APLFRNWAIH TGKHQPGVDK
     PDPKTWKANF RCAMNSLPDI EEVKDKSIKK GNNAFRVYRM LPLSERPSKK GKKPKTEKED
     RIKHIKQEPV ESSLGLSNGV SDLSPEYAVL TSAIKNEVDS TVNIIVVGQS HLDSNIEDQE
     IVTNPPDICQ VVEVTTESDE QPVSMSELYP LQISPVSSYA ESETTDSVPS DEESVEGRPH
     WRKRSIEGKQ YLSNMGTRST YLLPSMATFV TSNKPDLQVT IKEESCPVPF NSSWPTLPDL
     PLPPSVTPAP SSSRPDRETR ASVIKKTSDI TQARVKSC
//