ID   A0A384DP49_URSMA        Unreviewed;      1052 AA.
AC   A0A384DP49;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   03-AUG-2022, sequence version 2.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=ATPase MORC2 isoform X3 {ECO:0000313|RefSeq:XP_008708827.2};
GN   Name=MORC2 {ECO:0000313|RefSeq:XP_008708827.2};
OS   Ursus maritimus (Polar bear) (Thalarctos maritimus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus.
OX   NCBI_TaxID=29073 {ECO:0000313|Proteomes:UP000261680, ECO:0000313|RefSeq:XP_008708827.2};
RN   [1] {ECO:0000313|RefSeq:XP_008708827.2}
RP   IDENTIFICATION.
RC   TISSUE=Whole blood {ECO:0000313|RefSeq:XP_008708827.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_008708827.2; XM_008710605.2.
DR   AlphaFoldDB; A0A384DP49; -.
DR   OrthoDB; 933627at2759; -.
DR   Proteomes; UP000261680; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd16931; HATPase_MORC-like; 1.
DR   Gene3D; 3.30.40.100; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR041006; Morc_S5.
DR   InterPro; IPR011124; Znf_CW.
DR   PANTHER; PTHR23337:SF7; ATPASE MORC2; 1.
DR   PANTHER; PTHR23337; ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 1; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   Pfam; PF17942; Morc6_S5; 1.
DR   Pfam; PF07496; zf-CW; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS51050; ZF_CW; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261680};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00454}.
FT   DOMAIN          490..544
FT                   /note="CW-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51050"
FT   REGION          531..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          576..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          842..871
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          285..319
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          975..1009
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        533..562
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        612..636
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        674..695
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        739..796
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1052 AA;  120052 MW;  C17D0A92098299A2 CRC64;
     MAFTNYSSLN RAQLTFEYLH TNSTTHEFLF GALAELVDNA RDADATRIDI YAERREDLRG
     GFMLCFLDDG AGMDPSDAAS VIQFGKSAKR TPESTQIGQY GNGLKSGSMR IGKDFILFTK
     KEDTMTCLFL SRTFHEEEGI DEVIVPLPTW NARTREPVTD NVEKFAIETE LIYKYSPFHN
     EEEVMTQFMK IPGDSGTLVI IFNLKLMDNG EPELDIISNP RDIQMAETSP EGTKPERRSF
     RAYAAVLYID PRMRIFIHGH KVQTKRLSCC LYKPRMYKYT SSRFKTRAEQ EVKKAEHVAR
     IAEEKAREAE SKARTLEVRL GGDLTRDSRV MLRQVQNTAI TLRREADVKK RIKEAKQRAL
     KEPKELNFVF GVNIEHRDLD GMFIYNCSRL IKMYEKVGPQ LEGGMACGGV VGVVDVPYLV
     LEPTHNKQDF ADAKEYRHLL RAMGEHLAQY WKDIAIAQRG IIKFWDEFGY LSANWNQPPS
     SELRYKRRRA MEIPTTIQCD LCLKWRTLPF QLSSVEKDYP DTWVCSMNPD PEQDRCEASE
     QKQKVPLGTF RKDLKTQEEK QKQLTEKIRQ QQEKLEALQK TTPIRSQADL KKLPLEVTTR
     PSTEEPARRP QRPRSPPLPA VIKNAPSRPP SLQAPRPASQ PRKAPVISST PKPPALAARE
     EASTSRLLQP PEAPRKPTNT PVKTAPRPTP VVQPLSPSLL PNSRSPREVP APRAIKTPVV
     KKPEPPTKLS PTTPGRKRTL GVSDEEEAEE EAERRRERSK RGKFAVKEEK KDLNELSDSA
     GEEEPADLKR AQKDKGLHVE VRVNREWYTG RVTAVEVGKH VVRWKVKFDY VPTDTTPRDR
     WVEKGSEDVR LMKPPSPEYQ SPDTQQEGGE EEEEEVVVAQ QAVAMAEPST SDCIRIEPDT
     TAPSTNHETI DLLVQILRNC LRYFLPPSFP ISKKELSAMN SDELISFPLK EYFKQYEVGL
     QNLCHSYQSR ADSRAKASEE SLRTSERKLR ETEEKLQKLR TNIVALLQKH PDQEGWRWCG
     CLGLIPARPT DIDINTDDEL DAYIEDLITK GD
//