ID   A0A384I0E9_9ACTN        Unreviewed;       550 AA.
AC   A0A384I0E9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:PZT78149.1};
GN   ORFNames=DNK56_31450 {ECO:0000313|EMBL:PZT78149.1};
OS   Streptomyces sp. AC1-42W.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2218666 {ECO:0000313|EMBL:PZT78149.1, ECO:0000313|Proteomes:UP000249154};
RN   [1] {ECO:0000313|EMBL:PZT78149.1, ECO:0000313|Proteomes:UP000249154}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AC1-42W {ECO:0000313|EMBL:PZT78149.1,
RC   ECO:0000313|Proteomes:UP000249154};
RA   De Leon M.P., Montecillo A.D., Siringan M.A.T., Kim S.-G., Rosana A.R.R.;
RT   "Near complete genome sequences of Streptomyces sp. strains AC1-42W
RT   isolated from bat guano of Cabalyorisa Cave, Pangasinan, Philippines.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZT78149.1}.
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DR   EMBL; QKWY01000002; PZT78149.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A384I0E9; -.
DR   REBASE; 291326; M.Ssp142WORF31450P.
DR   Proteomes; UP000249154; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003356; DNA_methylase_A-5.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR42998:SF1; TYPE I RESTRICTION ENZYME HINDI METHYLASE SUBUNIT; 1.
DR   PANTHER; PTHR42998; TYPE I RESTRICTION ENZYME HINDVIIP M PROTEIN-RELATED; 1.
DR   Pfam; PF02384; N6_Mtase; 1.
DR   PRINTS; PR00507; N12N6MTFRASE.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:PZT78149.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249154};
KW   Transferase {ECO:0000313|EMBL:PZT78149.1}.
FT   DOMAIN          133..357
FT                   /note="DNA methylase adenine-specific"
FT                   /evidence="ECO:0000259|Pfam:PF02384"
SQ   SEQUENCE   550 AA;  59293 MW;  00CBA88ED8BEA7E2 CRC64;
     MKADAGRPHA DPLVTAAEIA RLAGVTRAAV SNWRRRYADF PAPATDSTSS PLFDLAEVRA
     WLDAQRKGQE MSAEVRLWQQ LRTDHGDDMI GGLTAVARLL ARREEPGDAA LRPLVDELAA
     DRSPAELLAG LTARFAESSG RAGSDGITSP HLVRAVRHFA GPDVPGRTVY DPACGTGSLL
     FAFRPGARSL AGQELDPARA RYAELRAEVT GPAGVTVRAG DSLRADALPE LRADLVVCEP
     PAGAADWGRE ELLLDPRWEF GVPSRAESEL AWLQHCYRHT APGGRVVVVM PASVAYRKAG
     RRIRAEIVRR GMLTEVVALP PGMAATHALP VHLWLLRRPA GPEDTADHVR MTDLSANAPD
     GPFEAADDQT APVARIDLLD DTVDLSPAAY ISARHTDFTA QYAATRAEIK ERLERLLDTL
     LPPLLEGTAE SFQERATVGL AELARAGLVE TTEGAVVSTS DQLDTDYING FLRGAANNRR
     STSASGTFRL DTRGARIPQM AVEEQRRYGS AFRALTEFEQ AVAQLARLSE RTTTLARTGL
     TTGTLRPPAP
//