ID A0A384I709_9ACTN Unreviewed; 757 AA.
AC A0A384I709;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=FdhF/YdeP family oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=DNK56_10625 {ECO:0000313|EMBL:PZT82478.1};
OS Streptomyces sp. AC1-42W.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2218666 {ECO:0000313|EMBL:PZT82478.1, ECO:0000313|Proteomes:UP000249154};
RN [1] {ECO:0000313|EMBL:PZT82478.1, ECO:0000313|Proteomes:UP000249154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC1-42W {ECO:0000313|EMBL:PZT82478.1,
RC ECO:0000313|Proteomes:UP000249154};
RA De Leon M.P., Montecillo A.D., Siringan M.A.T., Kim S.-G., Rosana A.R.R.;
RT "Near complete genome sequences of Streptomyces sp. strains AC1-42W
RT isolated from bat guano of Cabalyorisa Cave, Pangasinan, Philippines.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZT82478.1}.
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DR EMBL; QKWY01000001; PZT82478.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A384I709; -.
DR Proteomes; UP000249154; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000249154}.
FT DOMAIN 120..488
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 642..749
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 81778 MW; BA65785BCF59D4E0 CRC64;
MAGKPPAGDP VQDAPQVGPA KHAAAGLPAV AESLRVAQRQ MGLRRSAQTL LKVNQKDGFD
CPGCAWPEGD KRHVAEFCEN GVKAVAEEAT LRRVTPDFFA AHPVGDLAGR SGYWLGQQGR
ITQPVYLPEG ADRYQAVTWE RAFEIIAEEL GALSSPDEAV FYTSGRTSNE AAFLLQLFAR
EFGTNNLPDC SNMCHESSGS ALTETIGVGK GSVSLEDLHH ADLIIIAGQN PGTNHPRMLS
ALEQAKAAGA KIISVNPLPE AGLERFKNPQ TPHGMVRGTP LNDLFLQIRI GGDQALFRLL
NKLILDTEGA VDERFVAEHT HGYEEFAAAA AAADWDETLA ATGLDRAAIE QALALVLASE
RTVVCWAMGL TQHKHSVPTI REIVNFLLLR GNIGRPGAGV CPVRGHSNVQ GDRTMGIFER
PSTAFLDALD TEFGITSPRH HGYDVVRAIR ALRDGDAKVF FAMGGNFVAA TPDTDVTEAA
MRNARLTVHV STKLNRSHAV TGTRALILPT LGRTDKDVQA SGKQFVTVED SMSKVHASRG
NLTPASPHLL SEPAIVARLA RAVLGPGSAT PWEDFEHDYA TIRDRISRVV PGFENFNARI
AHPGGFTLPH APRDSRRFPT DTGRANFTAA PVEYPKPPEG RLLLQTLRSH DQYNTTIYGL
DDRYRGIKGG RRVVLVHPDD ATALGLADGS YTDLVSEWKD GVERRAPGFR VVHYPTARGC
AAAYYPETNV LVPLDSTADT SNTPASKSVV VRFEPAR
//
