ID   A0A384IJQ3_9ACTN        Unreviewed;       410 AA.
AC   A0A384IJQ3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Hyaluronate lyase {ECO:0000313|EMBL:PZT83410.1};
GN   ORFNames=DNK56_16285 {ECO:0000313|EMBL:PZT83410.1};
OS   Streptomyces sp. AC1-42W.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2218666 {ECO:0000313|EMBL:PZT83410.1, ECO:0000313|Proteomes:UP000249154};
RN   [1] {ECO:0000313|EMBL:PZT83410.1, ECO:0000313|Proteomes:UP000249154}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AC1-42W {ECO:0000313|EMBL:PZT83410.1,
RC   ECO:0000313|Proteomes:UP000249154};
RA   De Leon M.P., Montecillo A.D., Siringan M.A.T., Kim S.-G., Rosana A.R.R.;
RT   "Near complete genome sequences of Streptomyces sp. strains AC1-42W
RT   isolated from bat guano of Cabalyorisa Cave, Pangasinan, Philippines.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PZT83410.1}.
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DR   EMBL; QKWY01000001; PZT83410.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A384IJQ3; -.
DR   Proteomes; UP000249154; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR   NCBIfam; TIGR02032; GG-red-SF; 1.
DR   PANTHER; PTHR42685:SF22; CONDITIONED MEDIUM FACTOR RECEPTOR 1; 1.
DR   PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:PZT83410.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000249154}.
FT   DOMAIN          19..299
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
SQ   SEQUENCE   410 AA;  43561 MW;  C2B20D997784BB02 CRC64;
     MSSENADAGH EHEESSVWDV VVVGAGPAGA SAAYAAAVAG RKVLLLEKAE LPRYKTCGGG
     IIGYSRDALP PGFELPLRDR IHAVTFSLNG RLARTRRSKR MLFGLINRPE FDAGLVEQAQ
     KAGAELRTGA TVSRVEQHGA AVPDRRTVAV VLAGGETVLA RAVVGADGSA GRIGAHVGVK
     LDQVDLGLES EIPVPPTVAE DWAGRVLIDW GPMPGSYGWV FPKGDTLTVG VISARGDGAG
     TKRYLEDFVA RLGLAGFEPK ISSGHLTRCR SEDSPLSRGR VLVCGDAAGL LEPWTREGIS
     FALRSGRLAG EWAVRVAEAH DAVDARRQAL NYAFAIKAGL GVEMSVGRRM LKLFERRPGL
     LHAVLTGFRP AWNAFAGITR GTTSLAELVR SHPLAQRALS VMDRKAQTAE
//