ID A0A384IMT8_9ACTN Unreviewed; 486 AA.
AC A0A384IMT8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Glutamate synthase {ECO:0000313|EMBL:PZT82457.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:PZT82457.1};
GN Name=gltD {ECO:0000313|EMBL:PZT82457.1};
GN ORFNames=DNK56_10500 {ECO:0000313|EMBL:PZT82457.1};
OS Streptomyces sp. AC1-42W.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2218666 {ECO:0000313|EMBL:PZT82457.1, ECO:0000313|Proteomes:UP000249154};
RN [1] {ECO:0000313|EMBL:PZT82457.1, ECO:0000313|Proteomes:UP000249154}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC1-42W {ECO:0000313|EMBL:PZT82457.1,
RC ECO:0000313|Proteomes:UP000249154};
RA De Leon M.P., Montecillo A.D., Siringan M.A.T., Kim S.-G., Rosana A.R.R.;
RT "Near complete genome sequences of Streptomyces sp. strains AC1-42W
RT isolated from bat guano of Cabalyorisa Cave, Pangasinan, Philippines.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PZT82457.1}.
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DR EMBL; QKWY01000001; PZT82457.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A384IMT8; -.
DR Proteomes; UP000249154; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:PZT82457.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000249154}.
FT DOMAIN 40..130
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 146..456
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 486 AA; 52529 MW; F94FF0993DE87799 CRC64;
MADPKGFLTT GREVARTRPA DERVKDWNEV YVPGSLLPII SKQAGRCMDC GIPFCHNGCP
LGNLIPEWND YAYREDWSAA AERLHATNNF PEFTGRLCPA PCESACVLGI NQPAVTIKNV
EVSIIDKAWG NGDVTPRPPE RLSGKTVAVI GSGPAGLAAA QQLTRAGHTV AVYERADRIG
GLLRYGIPEF KMEKSHINRR IEQMRAEGTK FRTEIEIGRD IDAAKLRRRY DAVVIAAGAT
VSRDLPVPGR ELNGVHFAME YLPLANKVQE GDLTVSPITA EGKHVVVIGG GDTGADCVGT
AHRQGALSVT QLEIMPRPGE ERNANQPWPT FPMLYKVTSA HEEGGERVYS VSTTRFEGDE
DGNVQALHLV EVEFKDGKLE QKPGTERVIP AQLVTLAMGF TGTDQSNGLV QQFGLELDAR
GNIDRDADYA TNVDGVFVAG DAGRGQSLIV WAIAEGRSAA RGVDRFLTGA SALPAPIRPT
DRALTV
//
