ID A0A384K900_PLAKH Unreviewed; 1313 AA.
AC A0A384K900; A0A1A7VCW1; B3LAU0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 08-NOV-2023, entry version 24.
DE SubName: Full=LCCL domain-containing protein, putative {ECO:0000313|EMBL:CAA9990536.1};
GN ORFNames=PKNH_1351100 {ECO:0000313|EMBL:CAA9990536.1};
OS Plasmodium knowlesi (strain H).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5851 {ECO:0000313|EMBL:CAA9990536.1, ECO:0000313|Proteomes:UP000031513};
RN [1] {ECO:0000313|EMBL:CAA9990536.1, ECO:0000313|Proteomes:UP000031513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H {ECO:0000313|EMBL:CAA9990536.1,
RC ECO:0000313|Proteomes:UP000031513};
RA Pain A., Boehme U., Berry A.E., Mungall K., Finn R., Jackson A.P.,
RA Mourier T., Mistry J., Pasini E.M., Aslett M., Balasubrammaniam S.,
RA Borgwardt K., Brooks K., Carret C., Carver T.J., Cherevach I.,
RA Chillingworth T., Clarke T.G., Galinski M.R., Hall N., Harper D.,
RA Harris D., Hauser H., Ivens A., Janssen C.S., Keane T., Larke N., Lapp S.,
RA Marti M., Moule S., Meyer I.M., Ormond D., Peters N., Sanders M.,
RA Sanders S., Sergeant T.J., Simmonds M., Smith F., Squares R., Thurston S.,
RA Tivey A.R., Walker D., White B., Zuiderwijk E., Churcher C., Quail M.A.,
RA Cowman A.F., Turner C.M.R., Rajandream M.A., Kocken C.H.M., Thomas A.W.,
RA Newbold C.I., Barrell B.G., Berriman M.;
RT "The genome of Plasmodium knowlesi strain H, a zoonotic malaria parasite
RT with host range from monkey to man.";
RL Nature 455:799-803(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; AM910995; CAA9990536.1; -; Genomic_DNA.
DR RefSeq; XP_002260922.1; XM_002260886.1.
DR STRING; 5851.A0A384K900; -.
DR GeneID; 7322914; -.
DR KEGG; pkn:PKNH_1351100; -.
DR VEuPathDB; PlasmoDB:PKNH_1351100; -.
DR InParanoid; A0A384K900; -.
DR OMA; AGENLCG; -.
DR OrthoDB; 196370at2759; -.
DR Proteomes; UP000031513; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 4.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR Gene3D; 3.10.250.10; SRCR-like domain; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR017229; Scavenger_rcpt_PxSR.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR31331; LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630); 1.
DR PANTHER; PTHR31331:SF1; LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630); 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF03815; LCCL; 4.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF00530; SRCR; 2.
DR PIRSF; PIRSF037512; PxSR; 1.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00603; LCCL; 3.
DR SMART; SM00202; SR; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF69848; LCCL domain; 4.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF56487; SRCR-like; 2.
DR PROSITE; PS50820; LCCL; 4.
DR PROSITE; PS50095; PLAT; 1.
DR PROSITE; PS50287; SRCR_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000031513};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1313
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5030070542"
FT DOMAIN 165..274
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 282..371
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 409..522
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 536..650
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 694..795
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 1120..1163
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 1209..1306
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT REGION 654..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1290..1313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1313 AA; 144979 MW; 9A5D86592E192DE1 CRC64;
MVNTKCMKTL VVVHLLIQLL IQIAPLTTHA KEWCKVKFEF GKADYAECQS ETENIAKYMI
HTTPVISNDV DLYANVSLVM SNGYGFKTKE INIGSEEQGL LSKTFAVATD IGSPEYVHVK
INSVKKNWKC KKITIWKNYK YWVFDCAASL NDKNPQGTYF LSGNKMYTAF VKTGNEVQAG
TSGTVDIVLV GNNRRSNTKV LHEGFQSGVL KKIKFQASDV GKIEDIILTN NAKRDDPWYC
DFVKIKSDNK LYIFNVKSWI GHPYEKTVKI NIRADQSVDG GATKDIDCHI RGNDLINMNN
LPHALQSKVQ IFKVRCPQNC QNAEFASVEG SSIHPSSSSI CTSAIHDGSL TPSGGSIIIT
VGSDLHQYHS VKEKINNIEA IDVLTKVDEP NFSFYTYRLE SIDDVKSNVR IVDAFGKLSS
LGRLEIRRSD NTWGTVCKKG PNFTFSDDSA KRACADLGFA NGVYIKEMCF NLNGQNYCAG
YKYPFSSAGM VCSGNEKSLL NCNADDSSHC VDHHDDVIIQ CLNEQTNKES LSDGMIRLVD
ITGAPTTNGI GRLEMFYNGS FGSVCSEGWV KEGEKIACRE LGYTGLKGNG FSHHLCANIA
GENLCGHDAD KINAVNIKCK GDEKSLQNCA HETHEDIYCS HDEDIVLGCS GGEGGEEEEF
QGGSQENAQN NHHISTAPGL KKHFLTLEKK NFPRKIELTC FDKIVSIADL SAAQVGEVFL
ASCPEKCDEE IGIIKGTFLY TFDSPICKAA IHAGVLSSNV ADDIVLIISH KHHNFVGTKR
NNVESHEFAG TSKGFSISIP TRSIIQEERK SNHKYAEENS DKAFSDDDGL EDQHAEHSYS
LLAPPHIQRQ NGRLTTRVIG TQPTFQWIPP MGSPGFNGKE NDFVNCINLP NEKYIKSMSN
FTFIIYFTVS GGAGNWRTLL SHSLCDGISI SVNEENELII EQNCNPHLLK SKFKPVIGQT
YHLAVAFNKT NKSVTLYVNG KKLPTEKVKY DFTLNGDLVI GRSNQSTTDY FIGSIHLVEV
YKFVLADDEI KQLANAALSL DYLSGGSDSN YNDIRRTKRG KKTSGMNRKT VDGRECMTPC
KPQSIINKEL QINAEQINLS CKDDLLSHQF NSKIGSHFLV HCSDNCSKSN FIVKGSNNYY
TPDSSICKAA IHAGVYRPKR KNGDENNSFI LKIVNGLFEY KSARGHMGIV SKAERQSQLR
SFSIFPENDD NILSCSSNGH LFLNLPVGEK RTIICPSGCD KMEGKIWGTN VYTPSSTLCK
AAIHSGALSN QGGLVDMSIG SGVDKFTGAT QNGIESHSSA QHSRSLIFST HSQ
//
