ID A0A384KYI5_PLAKH Unreviewed; 529 AA.
AC A0A384KYI5; A0A1A7VU93; B3KZR8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Actin-like protein, putative {ECO:0000313|EMBL:CAA9986394.1};
GN ORFNames=PKNH_0212800 {ECO:0000313|EMBL:CAA9986394.1};
OS Plasmodium knowlesi (strain H).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5851 {ECO:0000313|EMBL:CAA9986394.1, ECO:0000313|Proteomes:UP000031513};
RN [1] {ECO:0000313|EMBL:CAA9986394.1, ECO:0000313|Proteomes:UP000031513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H {ECO:0000313|EMBL:CAA9986394.1,
RC ECO:0000313|Proteomes:UP000031513};
RA Pain A., Boehme U., Berry A.E., Mungall K., Finn R., Jackson A.P.,
RA Mourier T., Mistry J., Pasini E.M., Aslett M., Balasubrammaniam S.,
RA Borgwardt K., Brooks K., Carret C., Carver T.J., Cherevach I.,
RA Chillingworth T., Clarke T.G., Galinski M.R., Hall N., Harper D.,
RA Harris D., Hauser H., Ivens A., Janssen C.S., Keane T., Larke N., Lapp S.,
RA Marti M., Moule S., Meyer I.M., Ormond D., Peters N., Sanders M.,
RA Sanders S., Sergeant T.J., Simmonds M., Smith F., Squares R., Thurston S.,
RA Tivey A.R., Walker D., White B., Zuiderwijk E., Churcher C., Quail M.A.,
RA Cowman A.F., Turner C.M.R., Rajandream M.A., Kocken C.H.M., Thomas A.W.,
RA Newbold C.I., Barrell B.G., Berriman M.;
RT "The genome of Plasmodium knowlesi strain H, a zoonotic malaria parasite
RT with host range from monkey to man.";
RL Nature 455:799-803(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the actin family.
CC {ECO:0000256|ARBA:ARBA00006752}.
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DR EMBL; AM910984; CAA9986394.1; -; Genomic_DNA.
DR RefSeq; XP_002257800.1; XM_002257764.1.
DR AlphaFoldDB; A0A384KYI5; -.
DR STRING; 5851.A0A384KYI5; -.
DR GeneID; 7318695; -.
DR KEGG; pkn:PKNH_0212800; -.
DR VEuPathDB; PlasmoDB:PKNH_0212800; -.
DR InParanoid; A0A384KYI5; -.
DR OMA; GASICSN; -.
DR OrthoDB; 217775at2759; -.
DR Proteomes; UP000031513; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; ACTIN; 1.
DR PANTHER; PTHR11937:SF387; ACTIN; 1.
DR Pfam; PF00022; Actin; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Reference proteome {ECO:0000313|Proteomes:UP000031513}.
FT REGION 81..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 61854 MW; ADB3E9B9743096E6 CRC64;
MESRFKKNDS ENDYKYYVLQ IGRKYTYLGF SGLHKPLSVY RTPDFFRYNE SFHDYGKDKK
GVYDMLRSVS EGVGTSFRGC ASGYEDSSDQ QGEGLNLDEG EKGAKPDPNE DTLDQNQRLN
SICLNQPLPS MEGRKQEGSL IYHYEYKFHQ DVKLWRNFFE EFTFHIFRKL IKTNNKAKKV
IVLLNMFIPT IIKYSLCKTL IENYEYTSIS YINDLVSPLF LCNCNTCVVI DLGYLSCRLL
PVINGMPLYH HYTYVDNGGF YINMEIRRLL KEQYVRRARR RAMHDCEVSS ASFVQVSNEN
ILTNPQSTDN GYTATPHEEK PMEEEKGEKN TLEGLLNYYL DLYPLEEILN IIDIMPDDEI
ENIKMKYFYL KNEQGKLYTN KIVLYEFQNY QIIVEADTRW MACEILFTKD YEQNINSMFA
CILSKLHMFE FSAFHNVLLV GGCSNIKGIV SKIAQSLLNA LSEKKKTSLK DLENRVNFLF
PKISPNLRQF IGASICSNLE NLPDYTQEHI HNNVLYDHLN EDVYFTFKH
//
