ID A0A385BRW2_9FLAO Unreviewed; 312 AA.
AC A0A385BRW2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Mechanosensitive channel MscK {ECO:0000313|EMBL:AXP81872.1};
GN ORFNames=CJ739_2806 {ECO:0000313|EMBL:AXP81872.1};
OS Mariniflexile sp. TRM1-10.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Mariniflexile.
OX NCBI_TaxID=2027857 {ECO:0000313|EMBL:AXP81872.1, ECO:0000313|Proteomes:UP000259852};
RN [1] {ECO:0000313|Proteomes:UP000259852}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM1-10 {ECO:0000313|Proteomes:UP000259852};
RA Kim J.F., Kwak M.-J.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP022985; AXP81872.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A385BRW2; -.
DR KEGG; marf:CJ739_2806; -.
DR Proteomes; UP000259852; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000259852};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 122..188
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 198..279
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 312 AA; 35325 MW; 2F8F32D1EECDB6E8 CRC64;
MTQEFKMIAA AVAKSSFWND IKAFLNKHFD FSESISISVK DILIIITVIF ITTFVLRIVL
RIITRKLPED DKGKFNVVFG YFRWLIYLLI LLVTLHGVGV DVTAVFAASA ALMIGIGLAL
QTLFQDIISG VFILIDQTVH VGDIIELEGK IGRVEEIKLR TTRAVTIDNK VLIIPNHLYL
ENSLYNWTQN GFDTRESVEV GVAYGSDVQL VKKLLIEAAA VNKDVLYKDD IAVRFTNFGD
SSLDFKVIFT ISDSFNANAI RSDVRFEIDR LFRENNISIP FPQRDIHIIQ KPDQSVSLRL
DQSEFNTNLS KD
//
