ID A0A385Z046_9PSED Unreviewed; 726 AA.
AC A0A385Z046;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Bifunctional diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:AYC30982.1};
GN ORFNames=D3880_00645 {ECO:0000313|EMBL:AYC30982.1};
OS Pseudomonas cavernae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=2320867 {ECO:0000313|EMBL:AYC30982.1, ECO:0000313|Proteomes:UP000265560};
RN [1] {ECO:0000313|Proteomes:UP000265560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K2W31S-8 {ECO:0000313|Proteomes:UP000265560};
RA Zhu H.;
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP032419; AYC30982.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A385Z046; -.
DR KEGG; pcav:D3880_00645; -.
DR OrthoDB; 9804951at2; -.
DR Proteomes; UP000265560; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-UniRule.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR005330; MHYT_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF03707; MHYT; 3.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50924; MHYT; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Reference proteome {ECO:0000313|Proteomes:UP000265560};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00244};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU00244}.
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 60..84
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 159..182
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00244"
FT DOMAIN 24..218
FT /note="MHYT"
FT /evidence="ECO:0000259|PROSITE:PS50924"
FT DOMAIN 319..451
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 460..715
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 261..291
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 726 AA; 80169 MW; FE13677C6CDA895E CRC64;
MEWLGLRFLI GHPEGGQLVL ACSHDPGLVL VAYLVACIAG YATLSISDRL AYTQPQARRN
WYWVGGMCLG GGIWAMHFIA MLAFQAPIAI RYDLPTTILS FLVVVLAALL AMRSLARYRL
TAWQYLRTAL YISLGIVLMH YLGMAAIRSS ATLYYQPGLF ALSIVIAFLT SLAALWLALL
FRRRDSTLHQ MLKVIASLVM GGAIVSMHFT GMWALDLVVP SGTPLSLQSA QNATQLGLSI
AAIAFLSIGS GLGAAWADRK LQSKERDLQQ VNRLLNELDQ ARAMLQQAAH YDPLTNLLNR
RAFTEVFGEY LRSHEQRQQA LAVMFLDIDH FKRVNDCLGH DAGDQLLREV AVRIRGTLRP
QDVVARFGGD EFCILLSLNS GEEAHALAER IMQRLKEPIA LGGRCMVMST SIGISLSPHD
GETCDELLKH ADLALYQAKG SGRNAVHFFS QHLKHKVTLE LQLEEELRQA LLEDCGLLLH
YQPILEQASG TMTKLEALVR WQHPRLGLLA PDRFLGIAEA NGFIAELDAW VLRRACHDLA
LLGRHGFHGL RVAVNCSALD LNHDDLPEIV ASALNGANIR PQCLELEVTE NALMNNVNQA
LILLQCIREL GVSISIDDFG TGYSSLAYLK RLPLDTLKID RSFMLDIPAS SADREIVQAI
IGMAHTLHLQ VVAEGVETIE QLNFLRGLGC DFIQGYLLSK PLSLEQLGVF LGEHRSRSAD
ALVCPL
//
