ID A0A386HL95_9BACT Unreviewed; 807 AA.
AC A0A386HL95;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=D6B99_02970 {ECO:0000313|EMBL:AYD46668.1};
OS Arachidicoccus soli.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Arachidicoccus.
OX NCBI_TaxID=2341117 {ECO:0000313|EMBL:AYD46668.1, ECO:0000313|Proteomes:UP000266118};
RN [1] {ECO:0000313|EMBL:AYD46668.1, ECO:0000313|Proteomes:UP000266118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIS59-12 {ECO:0000313|EMBL:AYD46668.1,
RC ECO:0000313|Proteomes:UP000266118};
RA Weon H.-Y., Kwon S.-W., Lee S.A.;
RT "Arachidicoccus sp. nov., a bacterium isolated from soil.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP032489; AYD46668.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A386HL95; -.
DR KEGG; ark:D6B99_02970; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000266118; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266118};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 263..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 585..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 627..694
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 702..760
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 807 AA; 91771 MW; CD976E5CB59FBD4B CRC64;
MFFTKNIIRN LVIVAVLCIV YSCSYAQIQD STRPSRVSAA SAALGQDTLV SYIVKKVESY
SFKIKRDQST IKRDIKVAPI KEALPSIKKT LDAFSKRLNE KGRPMNLRGL NTSEIILQEN
SDRLLDLQST LNDYFNTLVL DNISLKQIRK DKLLRTYVSD TSLRNQMQSI IQNAIELDST
QKSILAKVTV LKNKVSVILL QSNDIISEIK YLTANVKIRM WGQEDESIFE DRPSEYNQSL
TAITLSSLYI NAKVLGNYLS NKWDSISFAF LLFVFIVFWC YSNIRRVKKM PEAKEVLAQV
FFLKRSVFAA CLMVFFTYLP FFFQNSQMSF LHTCELLRLI SLSYLLYPFL SKSFKPIWFI
FCLLWLYLAL DDLLLDPALA ERWMLIIADI LLIIICIKIL KNINDIFIKV ANSPATKPLV
IFCMAISFLS LLFNISGRPT LAKILGVTAI QSLFIGITLK VFSTIVIESI YLQSEAYKES
KFSEFINFKI LQHRLKKFLW FVAIIVWGIS LLIDFDLYAF ESNRFNLFLN ANRAIGNMNF
TYASVAIFIG IIWLSSIISS IVNFFFNQQR SKDVIKKNTI GSMMLLIRLA IWSIGFIIAV
AAAGIPLDKI SIMLGALGVG IGFGLQNITN NLVSGIILAF ERPIQIGDHI EIGNKAGVVD
EIGVRSSKIK SFDGSDIIVP NGDFLSQHVI NWTKQDRRKR LNFVIGVSYD SNLNSVKEII
EKTIEANENV LKENPPIILV HDFGASAINI DVFFWVEDLF IANSTKTRVM IEVYDNLIKN
KIVIPYPIVT VLQENKETDN KEVSDTK
//
