ID   A0A386QUR9_9VIRU        Unreviewed;      1211 AA.
AC   A0A386QUR9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Helicase-RNA polymerase {ECO:0000313|EMBL:AYE53918.1};
OS   Tea plant necrotic ring blotch virus.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Kitaviridae; Blunervirus; Blunervirus camelliae.
OX   NCBI_TaxID=2419939 {ECO:0000313|EMBL:AYE53918.1, ECO:0000313|Proteomes:UP000288873};
RN   [1] {ECO:0000313|EMBL:AYE53918.1, ECO:0000313|Proteomes:UP000288873}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=30254625; DOI=10.3389/fmicb.2018.02175;
RA   Hao X., Zhang W., Zhao F., Liu Y., Qian W., Wang Y., Wang L., Zeng J.,
RA   Yang Y., Wang X.;
RT   "Discovery of Plant Viruses From Tea Plant (Camellia sinensis (L.) O.
RT   Kuntze) by Metagenomic Sequencing.";
RL   Front. Microbiol. 9:2175-2175(2018).
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DR   EMBL; MG781153; AYE53918.1; -; Genomic_RNA.
DR   Proteomes; UP000288873; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR   CDD; cd23254; Kitaviridae_RdRp; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001788; RNA-dep_RNA_pol_alsuvir.
DR   InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR   Pfam; PF00978; RdRP_2; 1.
DR   Pfam; PF01443; Viral_helicase1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51657; PSRV_HELICASE; 1.
DR   PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:AYE53918.1};
KW   Hydrolase {ECO:0000313|EMBL:AYE53918.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000288873};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   DOMAIN          263..566
FT                   /note="(+)RNA virus helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51657"
FT   DOMAIN          964..1077
FT                   /note="RdRp catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50507"
SQ   SEQUENCE   1211 AA;  139146 MW;  F44E42D27C184AF5 CRC64;
     MTTIRADAFS TSRLLGEEFI LTPKSLVELD DVSLTFGDLL ERFLIEAPSL EYLGPEDTNL
     ILRVRITELR SEFFANSSSH DYYRPSDAEL ADMKSLVYPP RFKKVPRDDL PVDIHESSLM
     GPAAFLRELN SMHYNTEPQN QVQDVPKGND EEVFLDRSLE DVEIENIIDN TVLPTYAGEY
     MEIRLDPMLA VKEFLLYSRL YVKSMLHVPD CDKLIQKVSG VFVKGCVADL TNYRCFVDKR
     RKEVVFTSEY DSRRHTDIFT CEESRVCPYL NFSRLHPPVV ENLRNKCLLS ASFTQAGPGC
     GKTSRLISMA KNWPTTWLIL TSNKRTAVEI DTKLGRTFKN RVFTLDSYVM HKGYRCDTLF
     IDEVTLSHPG LVYIAIALSS CSRAHGFGDM MQIGFVDRKN LMHMRYSNCK NFYPVIDTLK
     HSYRMPPEIA KALSPAYVSA GLGDIESLNK SSTSVSSYPL SKFRPSPRYK LLVFCRDDKK
     LFPDYDVSTV HEFQGCESDH VQLYCSRSSK ILQNSLPHVI VALSRHRLRL SVYTDYDDTL
     LWNLLCSAKY GGDEISGGYT MMESKLLGWV YKKPHSMTTA PRSSSVPESW KDQDTLEIVR
     RESNENYLRV GQHALLRVDK SVSFKNFEET VAPMADVIIG RKLFIHDDAF SFEVHLAVRV
     LSKYKPRSIR VKSDPTAVSN EVFEFAQLNA LMPGYQIEPL IEDRFEVEEK PDDSDDDVDD
     ADTSDHLDVV QNFVDNLYTT DISRYNNEFD EFNFHHSDQV FPIDNIKFCE VRGTYEPSKF
     DKMRPALITP CPRVQMDTNI NAFHSALKRN LQVPKLTTVD DTYKVAERKV DELMGLCKGI
     CTDYMAPSVG SMQDWLNDQP NSIVNQLELE LAIHDRDVSW YSFMLKRCPK PELTPAAYSS
     YPAVQTILCQ DKEMNMYFCP VFRDLRDRII ATLDKRILFF TKCDDEGFSK QLNERLPVYE
     AENYNCAEFD MSKYDKSQGL LVLLIECMLL ERLGAGRRVS RLWFMAHACC KAVNPATGLT
     IKTVFQRKSG DASTYIGNTI ILMLSILDVV PIKDIALLLC SGDDSLLWTS KSVKSINFDV
     LTRRYNFEVK LFDFKYHYFC SKFIVPVCGK WCIVPDPLKR AVKLGRSDLA NKEHVEEYRI
     SFRDNVRIYR SFEVAYTTSQ AIQERYKTDY NSVFAILAMY QLSKQKHFGN LFYTEPGDVL
     CLDPSRSKLD M
//