ID A0A386QVG1_9VIRU Unreviewed; 1861 AA.
AC A0A386QVG1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Methyltransferase-helicase {ECO:0000313|EMBL:AYE53917.1};
OS Tea plant necrotic ring blotch virus.
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Kitaviridae; Blunervirus; Blunervirus camelliae.
OX NCBI_TaxID=2419939 {ECO:0000313|EMBL:AYE53917.1, ECO:0000313|Proteomes:UP000288873};
RN [1] {ECO:0000313|EMBL:AYE53917.1, ECO:0000313|Proteomes:UP000288873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=30254625; DOI=10.3389/fmicb.2018.02175;
RA Hao X., Zhang W., Zhao F., Liu Y., Qian W., Wang Y., Wang L., Zeng J.,
RA Yang Y., Wang X.;
RT "Discovery of Plant Viruses From Tea Plant (Camellia sinensis (L.) O.
RT Kuntze) by Metagenomic Sequencing.";
RL Front. Microbiol. 9:2175-2175(2018).
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DR EMBL; MG781152; AYE53917.1; -; Genomic_RNA.
DR Proteomes; UP000288873; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0008174; F:mRNA methyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd22792; OTU_RDRP-like; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR InterPro; IPR002588; Alphavirus-like_MT_dom.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01443; Viral_helicase1; 1.
DR Pfam; PF01660; Vmethyltransf; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51743; ALPHAVIRUS_MT; 1.
DR PROSITE; PS50802; OTU; 1.
DR PROSITE; PS51657; PSRV_HELICASE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AYE53917.1};
KW Helicase {ECO:0000313|EMBL:AYE53917.1};
KW Hydrolase {ECO:0000313|EMBL:AYE53917.1};
KW Methyltransferase {ECO:0000313|EMBL:AYE53917.1};
KW Nucleotide-binding {ECO:0000313|EMBL:AYE53917.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000288873};
KW Transferase {ECO:0000313|EMBL:AYE53917.1}.
FT DOMAIN 123..345
FT /note="Alphavirus-like MT"
FT /evidence="ECO:0000259|PROSITE:PS51743"
FT DOMAIN 691..828
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT DOMAIN 1477..1834
FT /note="(+)RNA virus helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51657"
SQ SEQUENCE 1861 AA; 211564 MW; BB6F832053176928 CRC64;
MADQEGPVVS PQLDATNYNL GFSPPLRRSE VQYGFTSAPG ENDRRHLGNV LKNVVGPDNA
KELMDRSSFD PLVTAAVAQE IVRRTHSQFV VDSSRKKYFT KYVSDSADLD ELQKNFPQFF
IVSDTCVPAL GHPYARETRM LEHKEIFEIN LGYNDGDTVP PGFDVLVKDI GGNPAVHDMQ
GRSLVHSCCP FLSGKDALRY DAWKEHVARH GKDAKVSEGA TKVSQTVVQK YPVTLDYLSP
VPKLTCTRLG QHCRVKSPIV TMIHSVYDMS LEQIGDCFDM ANCCKAYVTF LFDPRMFIQR
EGELGPHDCH WVRYGYGDSQ NINYSFRAGA CDSYTHRFSN IVSLVTSTYF VTPTGRVFVA
ERTLRNYTMS IHYVYCPNRL PCGEVSRVRM PFFDDKEAVF VATWWFNTQM VDNKVIPVVI
ETTQKFLHKV SNYAATLNDN KFNIDNVKKF AVSCNSDIVV GQVSSGGPKH SIEEIIQLVV
AIYMNTYDNN YYASQIVKRC VEDTAKVRRI NSSSYFVRML YKMFSLNYSN VDKFGRNDHP
LIKRNGEYVI NSTLDQSNQI AHIDRFDKLV EEYRDQSSGF LGINRILDKF EELFPAVKKK
YPIYFVRERF FTLTQAVEFG MVKNTPVSYT HARPVSPNMY LESAPALLYS NFTNAMKSDP
YIRDVIAVVQ SSTGKAYDAF RKPHVCRGSG FVSVEVPGDG NCFYHCLIKA LELSVSPNAV
RNRLSKSKYV DVLCSTVISD SLTIDLEARN ELINRLSPVQ VPSDRSRWAN DTVIALAALE
YSVAICVHKR STQYEYNGHM HSRQGNECSG TIIHLKYNDN HFALYVENVT GVSATLIDVD
LEIAGADEPQ NLEVSEDLMD VITVKNKVTN ETELPKSIYR SVYCYTNDYN PYNKLDKYGY
SSFYGPMLYT ALKDKKFGEN SRVLDVDSRN LSSLQVLCDN EFDEKFLNVT SLQLTSTSEE
IQTCRSYEKK LLWISSNNFE SRMRMVTRPF LPNEVYDLIT INPAYYSDKI GRICPKRHFD
HLKRTILTIS RLKKDGSLVL AMPFPIDQYV GSVIMYLRSK FESFSMTVPS VQPAYLTWWF
LKCENFVGPE CVIDDLEYHE IPTLPASING LLTSAHDSHS IKLKEEIDKI VNKKYTIPSK
SWVQKMLSLM PNRDDNLEAG YDESLLPEFS DEVAPAKLPV FGKDWVVKNY GEYAYAFDKV
RRTELIEKFS IEFRNSVYEL IGDPGQYLRD VAVSRIQGDK FLQQYAAVLV QNKSPILKLR
VHDVNKPVRS EHFYDRSILS KGFISRIKES LFPTDEYYTE QVGRPMNADM FDVSNVIPSI
VHIPLEKVGE PSSFDSSEPD DPQVVVNAGS GDKSEKVYWA ENRYSTDVNR NLELAMVEYS
DCISVHVDKV KANCRDTVRV LMAYRDYFSG NKHDVRKNLA PFVAQYNMDE FAFRYDGRYI
FGNDGVLGRY VFAFVSGPNR ELMTEMVKVD EKRILPKNFI YTSDLKVLME LDHMESFPTI
RHEPVVDVTM VQAGPGCGKT HDILEQLVQS VSTGSSVFAI MKNKENVESA KSRLRSMINS
KAIDQRKSAQ IMKRISSIDV VLKDPGKYTQ EFGVLDKVLV DEVITQPAGK IGFLAKSLNA
KLTVCYGDVA QISWACRLND FEPKYSEVSR ALPISGFLRD SFRCPGDICY FISRYYYDIA
KTLGIPCVDP HSVLRTKSKT RGVTIKLQHI GSVDNIPFDD KLQLLSFTQA DKEALIQKFG
RKKGLPIHTV HEYQGNENPR VALVRLSVHK NTDFPGDDGA FGSDSHIVSA ISRHTQSSVY
YTVNITDKLS KVINDINLNY PSWNMKRSDS VSEGNENRAS TSYSIENFSG IMDMYKSIPM
Y
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