ID   A0A387B7G8_9MICO        Unreviewed;       977 AA.
AC   A0A387B7G8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=MMPL family transporter {ECO:0000313|EMBL:AYF97135.1};
GN   ORFNames=D7I47_01975 {ECO:0000313|EMBL:AYF97135.1};
OS   Protaetiibacter intestinalis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Protaetiibacter.
OX   NCBI_TaxID=2419774 {ECO:0000313|EMBL:AYF97135.1, ECO:0000313|Proteomes:UP000278886};
RN   [1] {ECO:0000313|Proteomes:UP000278886}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2DFWR-13 {ECO:0000313|Proteomes:UP000278886};
RA   Heo J., Kim S.-J., Kwon S.-W.;
RT   "Genome sequencing of strain 2DFWR-13.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP032630; AYF97135.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A387B7G8; -.
DR   KEGG; lyd:D7I47_01975; -.
DR   OrthoDB; 7051771at2; -.
DR   Proteomes; UP000278886; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000278886};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        306..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        377..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        538..558
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        570..590
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        602..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        647..669
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          176..327
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   977 AA;  100846 MW;  E89035130408956F CRC64;
     MAILLSRIGR FAYRRAIPVL VAWLLLAAGA VLGGLALGGT MQDSFKIPGT ESQQAIDRLA
     AVFPQTAGAS AQMVVHSTDA MIASLGDDIE RVVTELGEVD GLENAVSPFS EYATDAISDD
     GMTAVVQLQF AGSSEEVTDA TLAAVQKVGD ELASDTVQVE YGGQVFQQFT MGLSVVEVIG
     VVFAAVVLIV TFGSLLAAGL PLLSALLALG ASMGGILALA AFTTLSTTTP MLALMIGLAV
     GIDYALFILS RHRAQLANGM DAEESAATAV ATAGGSVVFA GVTVMIALAG LLIVGIPFLG
     MMGVTAAFAV LLAMLAAITL LPAIMGLLKG RLAPKSGSRT ARRAQAQLHD VDAAEAGEGA
     APAAPHRKTL GERWVGLVLK APVAFILGVV ALLGVAAVPA AQLALALPDG GSLSEEETSR
     RAYDLIADAF GPGRNGPLIV TVDITQTTDV LDDLDRIADE LADVPGVASV GTPVPNPTVD
     TAIIQVIPET GPSDPETTAL VQHIRDLAPA IEDEFGTAVA VTGSTAVAID VSSRLDAALL
     PFGLVVVGLS IVLLMMVFRS IVVPLKAALG YLLSVLASFG IVVAVFQWGW GAELLHAVPG
     PILSFMPILL MAILFGLAMD YEVFLVSGMR EAYVHGASPK QAIRRGFSGA ARVVTAAALI
     MFFVFAAFVP EGASMIKVIA LGLAVGVAID AFLVRMTLVP AVMALFGKHA WYLPKWLDRI
     LPNVDVEGEG LRAHLDDLAW AQGRLGAGEA ITLEGLTGGV GDTRIGPYDA RVQAGSIALV
     GGDASRRRML AATVAGRLPA VEGRAQVAGR PLPSEASHVA RRVSFAEFGG AAREGELPLG
     ELLAERLRLT GRWYRTFTAR RRARVWVARI HDVVGASGSP VPIGWNTTPA SLPPVERAIA
     TLGIALSERT PVVVLDSVDP LPGADGGAGF LAAVDHLTPA ATTVVIGAAD AHRVAAPALS
     RPVGHFRPAD LTEGASR
//