ID A0A387B837_9MICO Unreviewed; 1497 AA.
AC A0A387B837;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=FHA domain-containing protein {ECO:0000313|EMBL:AYF98517.1};
GN ORFNames=D7I47_09765 {ECO:0000313|EMBL:AYF98517.1};
OS Protaetiibacter intestinalis.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Protaetiibacter.
OX NCBI_TaxID=2419774 {ECO:0000313|EMBL:AYF98517.1, ECO:0000313|Proteomes:UP000278886};
RN [1] {ECO:0000313|Proteomes:UP000278886}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2DFWR-13 {ECO:0000313|Proteomes:UP000278886};
RA Heo J., Kim S.-J., Kwon S.-W.;
RT "Genome sequencing of strain 2DFWR-13.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; CP032630; AYF98517.1; -; Genomic_DNA.
DR KEGG; lyd:D7I47_09765; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000278886; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd00060; FHA; 1.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR032030; YscD_cytoplasmic_dom.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR Pfam; PF16697; Yop-YscD_cpl; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50901; FTSK; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000278886};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..173
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 693..881
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1022..1213
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 943..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 711..718
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1039..1046
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1497 AA; 158073 MW; BD27711DD24665AD CRC64;
MKLKLTLQRP SGPEADIVVT ADAGATVADV AAGIQARDPY LAKLGATSGG PVTLTVTDAG
GTAPRVLDAD FAIAEAAVGS GATISIVPEG TSVQPAKTAA AAKLVVVEGP DAGAEFALVP
GTVFIGRDAA SADLVLADSL VSKRHARVDV FSHAIRLVDL NSANGIEVDG GLVTRVDLED
GDTVRLGDTV LRAAISAPVA AAPSGPPPGP IAFNRSPRVE SRYPGQEFAA PAPPAEQDAQ
PFPWLALVAP LAIGVVGIFF MNRNPAMLLL VLASPILMLG TWWTARSTRK RKRKLDIENF
DARSEALEKT LAEEVERERA VRLAESPSTA EVYQQALELG PLLWTRRPEH WQFLSVNLGI
GTMESRNRVT SSKEDTGLPE YVERVKKTQD AYRHIAGVPV TENLYFSGAL GIAGPQPVAA
DAARGLIVQL AGLHSPAELV VAAVVSSTWT NEFEWLKWLP HTASPHSPLD AVHLANSQAT
GGALLSAIEE LIATRAKDRE LRGAKMLEKS ALVAGASAGD GADEVAPPPA ATPAVALLIS
DDAPVDRARL VQLAERAADA GVYPIWVSPA QAQLPAVART YVAFGDDSTA QVGLVRLGDA
ITDVRTEPVT REQALWFARR LAPVTDAGAL VEDSSDLPRS IMMLSLVGPS LATSPSAAVG
RWRENDSIHD RSGGPLVRRR AGKLRAIVGS AGVDAMHLDL RTQGPHALVG GTTGSGKSEF
LQAWVLGMAA EYSPDRVTFL FVDYKGGSAF ADCVALPHCV GLVTDLSPHL VRRALTSLRA
ELHHREHLFN RKKAKDLLDL EKRGDPDAPP ALVLVIDEFA ALAGEVPEFV DGVVDIAQRG
RSLGIHLIMA TQRPAGVIKD NLRANTNLRI ALRMADESDS MDVVGDKIAG TFDPSIPGRG
IAKTGPGRLT PFQSAYAGGW TSDTPVAPSV EVAELRFGAE HQWEQPGKDE AVAAETQADP
GPTDQARLVA NLIAAAGEAR IPAPRRPWLD ELAPVFDLTR LHQRTDAELV LGVVDLPQLQ
RQQEVVFRPD VDGHIAYYGA GGAGKTVALR SLAAAAGITP RGGPVDVYGL DFGTGGLRML
EALPHVGSIV SGDDPERVVR LLRLLRDELE RRSAAYTAVD AGSIVDYRRI AGMPEERRIL
LLVDNFPSFK NDFEIGATRA PWYGVFQQIL GEGRGLGMHV AITADRPGSV PTGISSAFQR
RVALRLADEG GYMLLDAPAD ILSASSPPGR AVIDGAEAQL AIVGGEVGVA EQAKAITALG
EAIRRTGRAE AAEVGTLGTE IPAATLPSEV GGLPVLGVSD DTLQPVGFEP SGAIVLSGPP
ASGRTNALRW LIASVARAHP KIARYYFGSP RSEIGQRPGW EAKALTVEDA AALAKEVTAT
VAETGGDEKI LVVIEQIGDF LSTSADSAMV EMIKAIKRSD HLLIAENESG GWGSSWPLLQ
EVKAARTGFL LQPESMEGDT ILKTSLPRVS RGDFPPGRGF FIARGKAVRV QLPLAPD
//
