ID A0A387BV52_9MICO Unreviewed; 339 AA.
AC A0A387BV52;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Hydroxyacid dehydrogenase {ECO:0000313|EMBL:AYG02291.1};
GN ORFNames=D7I44_01255 {ECO:0000313|EMBL:AYG02291.1};
OS Gryllotalpicola protaetiae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Gryllotalpicola.
OX NCBI_TaxID=2419771 {ECO:0000313|EMBL:AYG02291.1, ECO:0000313|Proteomes:UP000275069};
RN [1] {ECO:0000313|EMBL:AYG02291.1, ECO:0000313|Proteomes:UP000275069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2DFW10M-5 {ECO:0000313|EMBL:AYG02291.1,
RC ECO:0000313|Proteomes:UP000275069};
RA Heo J., Kim S.-J., Kwon S.-W.;
RT "Genome sequencing of strain 2DFW10M-5.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CP032624; AYG02291.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A387BV52; -.
DR KEGG; gry:D7I44_01255; -.
DR OrthoDB; 4324715at2; -.
DR Proteomes; UP000275069; Chromosome.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12167; 2-Hacid_dh_8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000275069}.
FT DOMAIN 41..326
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 135..299
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 339 AA; 35982 MW; 5DF0EB9E816D29AB CRC64;
MTTQRVPEAL ILMSREAFDA QFDDARLARL RALAALPEPI WVDDLDDPAL TARLTGVEVL
ITGWGAPLLD EARLDRMPQL KVMLHGAGTI RSMVTDAFWK RGIAAANVAD VNAVPVAEFT
LAAVIMAGKR APFLAADATV HAGWESIDRF GQLGNVGRTV GVVGFSRVGR RVVSALQQLE
ALTCLVYDPY ADAGEVTAAG GRLVGTLDEL LPRVDVLSLH VPALPETRNM IGAAELAALP
DHATVINTAR GSVIDTAALE AECASGRLNA IIDVTEPEPL PAASVLFSLP NVMVTPHIAG
SLGNELYRMT DAALDELERY VRGLPLSAAI SSEDLRLSA
//
